15 items (Oryctolagus cuniculus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Predicted Interactions

gene neighborhood

gene fusions

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textmining

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protein homology

Your Input:
	PAX5	Paired box 5. (371 aa)
	EBF4	EBF family member 4. (572 aa)
	IGHM-2	Ig-like domain-containing protein. (167 aa)
	RAG1	V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1128 aa)
	RAG2	V(D)J recombination-activating protein 2; Core component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T- cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. DNA cleavage by the RAG complex occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the pho [...] (527 aa)
	IGHM-3	Ig-like domain-containing protein. (167 aa)
	KIT	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (970 aa)
	CD19	CD19 molecule. (573 aa)
	IL7	Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (175 aa)
	EBF2	EBF transcription factor 2. (609 aa)
	FLT3	Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (993 aa)
	IRS1	Insulin receptor substrate 1. (1220 aa)
	EBF3	EBF transcription factor 3. (520 aa)
	EBF1	EBF transcription factor 1. (591 aa)
	IRF4	Interferon regulatory factor 4. (451 aa)

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD19	EBF1	ENSOCUP00000036537	ENSOCUP00000007763	CD19 molecule.	EBF transcription factor 1.	0.597
CD19	FLT3	ENSOCUP00000036537	ENSOCUP00000004237	CD19 molecule.	Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.698
CD19	IGHM-2	ENSOCUP00000036537	ENSOCUP00000018495	CD19 molecule.	Ig-like domain-containing protein.	0.775
CD19	IGHM-3	ENSOCUP00000036537	ENSOCUP00000025645	CD19 molecule.	Ig-like domain-containing protein.	0.775
CD19	IL7	ENSOCUP00000036537	ENSOCUP00000038193	CD19 molecule.	Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family.	0.789
CD19	IRF4	ENSOCUP00000036537	ENSOCUP00000008085	CD19 molecule.	Interferon regulatory factor 4.	0.722
CD19	KIT	ENSOCUP00000036537	ENSOCUP00000034895	CD19 molecule.	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.773
CD19	PAX5	ENSOCUP00000036537	ENSOCUP00000010574	CD19 molecule.	Paired box 5.	0.833
CD19	RAG1	ENSOCUP00000036537	ENSOCUP00000020586	CD19 molecule.	V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...]	0.749
CD19	RAG2	ENSOCUP00000036537	ENSOCUP00000020912	CD19 molecule.	V(D)J recombination-activating protein 2; Core component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T- cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. DNA cleavage by the RAG complex occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the pho [...]	0.734
EBF1	CD19	ENSOCUP00000007763	ENSOCUP00000036537	EBF transcription factor 1.	CD19 molecule.	0.597
EBF1	FLT3	ENSOCUP00000007763	ENSOCUP00000004237	EBF transcription factor 1.	Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.414
EBF1	IGHM-2	ENSOCUP00000007763	ENSOCUP00000018495	EBF transcription factor 1.	Ig-like domain-containing protein.	0.540
EBF1	IGHM-3	ENSOCUP00000007763	ENSOCUP00000025645	EBF transcription factor 1.	Ig-like domain-containing protein.	0.540
EBF1	IL7	ENSOCUP00000007763	ENSOCUP00000038193	EBF transcription factor 1.	Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family.	0.530
EBF1	IRF4	ENSOCUP00000007763	ENSOCUP00000008085	EBF transcription factor 1.	Interferon regulatory factor 4.	0.548
EBF1	PAX5	ENSOCUP00000007763	ENSOCUP00000010574	EBF transcription factor 1.	Paired box 5.	0.831
EBF1	RAG1	ENSOCUP00000007763	ENSOCUP00000020586	EBF transcription factor 1.	V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...]	0.595
EBF1	RAG2	ENSOCUP00000007763	ENSOCUP00000020912	EBF transcription factor 1.	V(D)J recombination-activating protein 2; Core component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T- cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. DNA cleavage by the RAG complex occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the pho [...]	0.533
EBF2	PAX5	ENSOCUP00000045602	ENSOCUP00000010574	EBF transcription factor 2.	Paired box 5.	0.433