STRINGSTRING
STAT1 STAT1 LIF LIF STAT5B STAT5B CNTF CNTF CTF1 CTF1 STAT6 STAT6 OSM OSM STAT3 STAT3 OSMR OSMR ANGPT2 ANGPT2 ALB ALB IL6 IL6 VWF VWF STAT5A STAT5A STAT4 STAT4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STAT1Signal transducer and activator of transcription. (879 aa)
LIFLIF interleukin 6 family cytokine. (203 aa)
STAT5BSignal transducer and activator of transcription. (786 aa)
CNTFCiliary neurotrophic factor; CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy. (199 aa)
CTF1Cardiotrophin 1. (190 aa)
STAT6Signal transducer and activator of transcription. (842 aa)
OSMUncharacterized protein. (333 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
OSMROncostatin M receptor. (1088 aa)
ANGPT2Angiopoietin 2. (496 aa)
ALBSerum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] (608 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (241 aa)
VWFVon Willebrand factor. (2788 aa)
STAT5ASignal transducer and activator of transcription. (793 aa)
STAT4Signal transducer and activator of transcription. (752 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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