(9 nodes) (2010) Cortical mechanics and meiosis II completion in mammalian oocytes are mediated by myosin-II and Ezrin-Radixin-Moesin (ERM) proteins. network (Oryctolagus cuniculus)

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Your Input:
	FMN2	Formin 2. (1828 aa)
	CDC42-2	Uncharacterized protein. (222 aa)
	CDC42	Uncharacterized protein. (191 aa)
	PRKACB	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
	EZR	Ezrin; Probably involved in connections of major cytoskeletal structures to the plasma membrane (By similarity). In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis (By similarity). (653 aa)
	RDX	Radixin. (643 aa)
	MSN	FERM domain-containing protein. (577 aa)
	CDK1	Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
	MYC	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (438 aa)

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	EZR	ENSOCUP00000047724	ENSOCUP00000040029	Uncharacterized protein.	Ezrin; Probably involved in connections of major cytoskeletal structures to the plasma membrane (By similarity). In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis (By similarity).	0.793
CDC42	FMN2	ENSOCUP00000047724	ENSOCUP00000023697	Uncharacterized protein.	Formin 2.	0.644
CDC42	MSN	ENSOCUP00000047724	ENSOCUP00000000131	Uncharacterized protein.	FERM domain-containing protein.	0.783
CDC42	MYC	ENSOCUP00000047724	ENSOCUP00000012281	Uncharacterized protein.	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.	0.668
CDC42	PRKACB	ENSOCUP00000047724	ENSOCUP00000043583	Uncharacterized protein.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.610
CDC42	RDX	ENSOCUP00000047724	ENSOCUP00000037499	Uncharacterized protein.	Radixin.	0.783
CDC42-2	EZR	ENSOCUP00000025997	ENSOCUP00000040029	Uncharacterized protein.	Ezrin; Probably involved in connections of major cytoskeletal structures to the plasma membrane (By similarity). In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis (By similarity).	0.793
CDC42-2	FMN2	ENSOCUP00000025997	ENSOCUP00000023697	Uncharacterized protein.	Formin 2.	0.642
CDC42-2	MSN	ENSOCUP00000025997	ENSOCUP00000000131	Uncharacterized protein.	FERM domain-containing protein.	0.783
CDC42-2	MYC	ENSOCUP00000025997	ENSOCUP00000012281	Uncharacterized protein.	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.	0.668
CDC42-2	PRKACB	ENSOCUP00000025997	ENSOCUP00000043583	Uncharacterized protein.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.610
CDC42-2	RDX	ENSOCUP00000025997	ENSOCUP00000037499	Uncharacterized protein.	Radixin.	0.783
CDK1	MYC	ENSOCUP00000002479	ENSOCUP00000012281	Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.	0.747
EZR	CDC42	ENSOCUP00000040029	ENSOCUP00000047724	Ezrin; Probably involved in connections of major cytoskeletal structures to the plasma membrane (By similarity). In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis (By similarity).	Uncharacterized protein.	0.793
EZR	CDC42-2	ENSOCUP00000040029	ENSOCUP00000025997	Ezrin; Probably involved in connections of major cytoskeletal structures to the plasma membrane (By similarity). In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis (By similarity).	Uncharacterized protein.	0.793
EZR	MSN	ENSOCUP00000040029	ENSOCUP00000000131	Ezrin; Probably involved in connections of major cytoskeletal structures to the plasma membrane (By similarity). In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis (By similarity).	FERM domain-containing protein.	0.999
EZR	PRKACB	ENSOCUP00000040029	ENSOCUP00000043583	Ezrin; Probably involved in connections of major cytoskeletal structures to the plasma membrane (By similarity). In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis (By similarity).	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.979
EZR	RDX	ENSOCUP00000040029	ENSOCUP00000037499	Ezrin; Probably involved in connections of major cytoskeletal structures to the plasma membrane (By similarity). In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis (By similarity).	Radixin.	0.999
FMN2	CDC42	ENSOCUP00000023697	ENSOCUP00000047724	Formin 2.	Uncharacterized protein.	0.644
FMN2	CDC42-2	ENSOCUP00000023697	ENSOCUP00000025997	Formin 2.	Uncharacterized protein.	0.642