Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CUL3 | CUL4A | ENSOCUP00000031324 | ENSOCUP00000008283 | Cullin 3; Belongs to the cullin family. | Cullin 4A; Belongs to the cullin family. | 0.756 |
| CUL3 | CUL4B | ENSOCUP00000031324 | ENSOCUP00000040452 | Cullin 3; Belongs to the cullin family. | Cullin 4B; Belongs to the cullin family. | 0.692 |
| CUL3 | CUL5 | ENSOCUP00000031324 | ENSOCUP00000009389 | Cullin 3; Belongs to the cullin family. | Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...] | 0.903 |
| CUL3 | GAPDH | ENSOCUP00000031324 | ENSOCUP00000044112 | Cullin 3; Belongs to the cullin family. | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] | 0.538 |
| CUL3 | NEDD8 | ENSOCUP00000031324 | ENSOCUP00000002526 | Cullin 3; Belongs to the cullin family. | NEDD8; Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins (By similarity). | 0.995 |
| CUL3 | SKP1 | ENSOCUP00000031324 | ENSOCUP00000020468 | Cullin 3; Belongs to the cullin family. | Uncharacterized protein; Belongs to the SKP1 family. | 0.940 |
| CUL3 | SKP2 | ENSOCUP00000031324 | ENSOCUP00000007901 | Cullin 3; Belongs to the cullin family. | F-box domain-containing protein. | 0.941 |
| CUL3 | UBA3 | ENSOCUP00000031324 | ENSOCUP00000007065 | Cullin 3; Belongs to the cullin family. | Ubiquitin like modifier activating enzyme 3. | 0.934 |
| CUL4A | CUL3 | ENSOCUP00000008283 | ENSOCUP00000031324 | Cullin 4A; Belongs to the cullin family. | Cullin 3; Belongs to the cullin family. | 0.756 |
| CUL4A | CUL4B | ENSOCUP00000008283 | ENSOCUP00000040452 | Cullin 4A; Belongs to the cullin family. | Cullin 4B; Belongs to the cullin family. | 0.996 |
| CUL4A | CUL5 | ENSOCUP00000008283 | ENSOCUP00000009389 | Cullin 4A; Belongs to the cullin family. | Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...] | 0.683 |
| CUL4A | GAPDH | ENSOCUP00000008283 | ENSOCUP00000044112 | Cullin 4A; Belongs to the cullin family. | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] | 0.444 |
| CUL4A | NEDD8 | ENSOCUP00000008283 | ENSOCUP00000002526 | Cullin 4A; Belongs to the cullin family. | NEDD8; Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins (By similarity). | 0.973 |
| CUL4A | SKP1 | ENSOCUP00000008283 | ENSOCUP00000020468 | Cullin 4A; Belongs to the cullin family. | Uncharacterized protein; Belongs to the SKP1 family. | 0.766 |
| CUL4A | SKP2 | ENSOCUP00000008283 | ENSOCUP00000007901 | Cullin 4A; Belongs to the cullin family. | F-box domain-containing protein. | 0.836 |
| CUL4A | UBA3 | ENSOCUP00000008283 | ENSOCUP00000007065 | Cullin 4A; Belongs to the cullin family. | Ubiquitin like modifier activating enzyme 3. | 0.795 |
| CUL4B | CUL3 | ENSOCUP00000040452 | ENSOCUP00000031324 | Cullin 4B; Belongs to the cullin family. | Cullin 3; Belongs to the cullin family. | 0.692 |
| CUL4B | CUL4A | ENSOCUP00000040452 | ENSOCUP00000008283 | Cullin 4B; Belongs to the cullin family. | Cullin 4A; Belongs to the cullin family. | 0.996 |
| CUL4B | CUL5 | ENSOCUP00000040452 | ENSOCUP00000009389 | Cullin 4B; Belongs to the cullin family. | Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...] | 0.755 |
| CUL4B | NEDD8 | ENSOCUP00000040452 | ENSOCUP00000002526 | Cullin 4B; Belongs to the cullin family. | NEDD8; Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins (By similarity). | 0.957 |
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