STRINGSTRING
CDKN2B CDKN2B PAX5 PAX5 FHIT FHIT IRF4 IRF4 EBF1 EBF1 NF1 NF1 MLLT3 MLLT3 MS4A1 MS4A1 GRIK2 GRIK2 SP7 SP7 BLNK BLNK TENT5D TENT5D IGHM-3 IGHM-3 CD4 CD4 CD34 CD34 KIT KIT DPF3 DPF3 CD19 CD19 RUNX1T1 RUNX1T1 CD38 CD38 RAP1B RAP1B MME MME MPO MPO ZCCHC7 ZCCHC7 NR3C1 NR3C1 MEF2C MEF2C CD44 CD44 L3MBTL3 L3MBTL3 GATA1 GATA1 LEF1 LEF1 RASGRF1 RASGRF1 CNR2 CNR2 CCR6 CCR6 ZHX2 ZHX2 CEBPE CEBPE CXCR5 CXCR5 IGHM-2 IGHM-2 SPIB SPIB TCF12 TCF12 ANPEP ANPEP TBL1XR1 TBL1XR1 ETV6 ETV6 EPOR EPOR IKZF1 IKZF1 FOXO1 FOXO1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CDKN2BCyclin dependent kinase inhibitor 2B. (138 aa)
PAX5Paired box 5. (371 aa)
FHITHIT domain-containing protein. (173 aa)
IRF4Interferon regulatory factor 4. (451 aa)
EBF1EBF transcription factor 1. (591 aa)
NF1Neurofibromin 1. (2841 aa)
MLLT3MLLT3 super elongation complex subunit. (572 aa)
MS4A1Membrane spanning 4-domains A1. (298 aa)
GRIK2Glutamate ionotropic receptor kainate type subunit 2. (908 aa)
SP7Sp7 transcription factor. (431 aa)
BLNKB cell linker. (274 aa)
TENT5DTerminal nucleotidyltransferase 5D. (344 aa)
IGHM-3Ig-like domain-containing protein. (167 aa)
CD4T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (536 aa)
CD34CD34 molecule. (415 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (970 aa)
DPF3Double PHD fingers 3. (388 aa)
CD19CD19 molecule. (573 aa)
RUNX1T1RUNX1 partner transcriptional co-repressor 1. (662 aa)
CD38ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; Synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. (299 aa)
RAP1BUncharacterized protein. (184 aa)
MMENeprilysin; Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers. Belongs to the peptidase M13 family. (750 aa)
MPOMyeloperoxidase. (725 aa)
ZCCHC7Zinc finger CCHC-type containing 7. (634 aa)
NR3C1Glucocorticoid receptor; Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Involved in chromatin remodeling. Plays a role in rapid mRNA degradation by binding to the 5' UTR of target mRNAs and interacting with PNRC2 in a ligand-dependent manner which recruits the RNA helicase UPF1 and the mRNA-decapping enzyme DCP [...] (773 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
CD44CD44 molecule (Indian blood group). (761 aa)
L3MBTL3L3MBTL histone methyl-lysine binding protein 3. (780 aa)
GATA1GATA binding protein 1. (413 aa)
LEF1Lymphoid enhancer binding factor 1. (414 aa)
RASGRF1Ras protein specific guanine nucleotide releasing factor 1. (1139 aa)
CNR2Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. (517 aa)
CCR6C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (375 aa)
ZHX2Zinc fingers and homeoboxes 2. (785 aa)
CEBPECCAAT/enhancer-binding protein. (281 aa)
CXCR5C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family. (374 aa)
IGHM-2Ig-like domain-containing protein. (167 aa)
SPIBETS domain-containing protein. (158 aa)
TCF12Transcription factor 12. (675 aa)
ANPEPAminopeptidase N; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding [...] (718 aa)
TBL1XR1Transducin beta like 1 X-linked receptor 1. (514 aa)
ETV6ETS variant 6. (508 aa)
EPORErythropoietin receptor. (554 aa)
IKZF1IKAROS family zinc finger 1. (515 aa)
FOXO1Fork-head domain-containing protein. (613 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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