30 items (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ALK	Tyrosine-protein kinase receptor. (1448 aa)
	CRKL	CRK like proto-oncogene, adaptor protein. (303 aa)
	NUP214	Nucleoporin 214. (2126 aa)
	RANBP2	Uncharacterized protein. (1642 aa)
	PDGFRB	Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1147 aa)
	TSHZ2	Teashirt zinc finger homeobox 2. (1036 aa)
	SH2B3	SH2B adaptor protein 3. (354 aa)
	DOCK8	Dedicator of cytokinesis 8; Belongs to the DOCK family. (2102 aa)
	NUP88	Nucleoporin 88. (740 aa)
	FLT3	Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (993 aa)
	ZNF292	Zinc finger protein 292. (2902 aa)
	EBF1	EBF transcription factor 1. (591 aa)
	IL7R	Interleukin 7 receptor. (458 aa)
	STRN3	Striatin 3. (713 aa)
	PAX5	Paired box 5. (371 aa)
	RUNX1	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (466 aa)
	FEM1C	Fem-1 homolog C. (617 aa)
	IKZF1	IKAROS family zinc finger 1. (515 aa)
	EPOR	Erythropoietin receptor. (554 aa)
	ETV6	ETS variant 6. (508 aa)
	JAK2	Tyrosine-protein kinase. (1132 aa)
	SYNCRIP	Uncharacterized protein. (623 aa)
	P2RY8	P2Y receptor family member 8; Belongs to the G-protein coupled receptor 1 family. (382 aa)
	BCR	BCR activator of RhoGEF and GTPase. (1192 aa)
	SEMA6A	Semaphorin 6A; Belongs to the semaphorin family. (1038 aa)
	CD19	CD19 molecule. (573 aa)
	ABL1	Tyrosine-protein kinase. (1118 aa)
	PBX1	PBX homeobox 1. (430 aa)
	SRC	Tyrosine-protein kinase. (589 aa)
	ZCCHC7	Zinc finger CCHC-type containing 7. (634 aa)

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	BCR	ENSOCUP00000038489	ENSOCUP00000027066	Tyrosine-protein kinase.	BCR activator of RhoGEF and GTPase.	0.948
ABL1	CRKL	ENSOCUP00000038489	ENSOCUP00000000710	Tyrosine-protein kinase.	CRK like proto-oncogene, adaptor protein.	0.987
ABL1	EPOR	ENSOCUP00000038489	ENSOCUP00000013491	Tyrosine-protein kinase.	Erythropoietin receptor.	0.412
ABL1	ETV6	ENSOCUP00000038489	ENSOCUP00000014459	Tyrosine-protein kinase.	ETS variant 6.	0.805
ABL1	FLT3	ENSOCUP00000038489	ENSOCUP00000004237	Tyrosine-protein kinase.	Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.562
ABL1	IKZF1	ENSOCUP00000038489	ENSOCUP00000012401	Tyrosine-protein kinase.	IKAROS family zinc finger 1.	0.566
ABL1	JAK2	ENSOCUP00000038489	ENSOCUP00000014491	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.579
ABL1	NUP214	ENSOCUP00000038489	ENSOCUP00000000870	Tyrosine-protein kinase.	Nucleoporin 214.	0.822
ABL1	PAX5	ENSOCUP00000038489	ENSOCUP00000010574	Tyrosine-protein kinase.	Paired box 5.	0.449
ABL1	PBX1	ENSOCUP00000038489	ENSOCUP00000040408	Tyrosine-protein kinase.	PBX homeobox 1.	0.400
ABL1	PDGFRB	ENSOCUP00000038489	ENSOCUP00000001483	Tyrosine-protein kinase.	Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells.	0.449
ABL1	RANBP2	ENSOCUP00000038489	ENSOCUP00000001015	Tyrosine-protein kinase.	Uncharacterized protein.	0.459
ABL1	RUNX1	ENSOCUP00000038489	ENSOCUP00000011814	Tyrosine-protein kinase.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.697
ABL1	SH2B3	ENSOCUP00000038489	ENSOCUP00000002476	Tyrosine-protein kinase.	SH2B adaptor protein 3.	0.468
ALK	CRKL	ENSOCUP00000045410	ENSOCUP00000000710	Tyrosine-protein kinase receptor.	CRK like proto-oncogene, adaptor protein.	0.581
ALK	ETV6	ENSOCUP00000045410	ENSOCUP00000014459	Tyrosine-protein kinase receptor.	ETS variant 6.	0.528
ALK	JAK2	ENSOCUP00000045410	ENSOCUP00000014491	Tyrosine-protein kinase receptor.	Tyrosine-protein kinase.	0.532
ALK	SRC	ENSOCUP00000045410	ENSOCUP00000043750	Tyrosine-protein kinase receptor.	Tyrosine-protein kinase.	0.433
BCR	ABL1	ENSOCUP00000027066	ENSOCUP00000038489	BCR activator of RhoGEF and GTPase.	Tyrosine-protein kinase.	0.948
BCR	CRKL	ENSOCUP00000027066	ENSOCUP00000000710	BCR activator of RhoGEF and GTPase.	CRK like proto-oncogene, adaptor protein.	0.940