STRINGSTRING
SRC SRC EZH2 EZH2 IL7 IL7 CD19 CD19 CXCR4 CXCR4 FOXP1 FOXP1 EBF1 EBF1 DICER1 DICER1 IL7R IL7R MCL1 MCL1 PAX5 PAX5 SOX11 SOX11 RAG1 RAG1 VAV1 VAV1 BCR BCR KIT KIT BCL2 BCL2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SRCTyrosine-protein kinase. (589 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (769 aa)
IL7Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (175 aa)
CD19CD19 molecule. (573 aa)
CXCR4C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (366 aa)
FOXP1Fork-head domain-containing protein. (714 aa)
EBF1EBF transcription factor 1. (591 aa)
DICER1Uncharacterized protein. (821 aa)
IL7RInterleukin 7 receptor. (458 aa)
MCL1MCL1 apoptosis regulator, BCL2 family member. (352 aa)
PAX5Paired box 5. (371 aa)
SOX11Transcription factor SOX. (446 aa)
RAG1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1128 aa)
VAV1Vav guanine nucleotide exchange factor 1. (681 aa)
BCRBCR activator of RhoGEF and GTPase. (1192 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (970 aa)
BCL2BH4_2 domain-containing protein. (389 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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