STRINGSTRING
PPARG PPARG PCGF1 PCGF1 CD40 CD40 PXDN PXDN EBF2 EBF2 BGLAP BGLAP ALPL ALPL PXDNL PXDNL EBF1 EBF1 RUNX2 RUNX2 PAX5 PAX5 COL1A1 COL1A1 IGLL1 IGLL1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
PCGF1Polycomb group ring finger 1. (263 aa)
CD40Uncharacterized protein. (494 aa)
PXDNPeroxidasin. (1411 aa)
EBF2EBF transcription factor 2. (609 aa)
BGLAPOsteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. (100 aa)
ALPLAlkaline phosphatase. (558 aa)
PXDNLPeroxidasin like. (1467 aa)
EBF1EBF transcription factor 1. (591 aa)
RUNX2RUNX family transcription factor 2. (343 aa)
PAX5Paired box 5. (371 aa)
COL1A1Collagen alpha-1(I) chain. (1348 aa)
IGLL1Lambda5. (208 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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