STRINGSTRING
BLNK BLNK IRF8 IRF8 GFI1B GFI1B LMNB1 LMNB1 EBF1 EBF1 IRF4 IRF4 IL7R IL7R PAX5 PAX5 FOXO1 FOXO1 SYK SYK SPIB SPIB HPRT1 HPRT1 IGHM-2 IGHM-2 RAG1 RAG1 RAG2 RAG2 IGHM-3 IGHM-3 CD19 CD19 IL7 IL7 CCND3 CCND3 EZH2 EZH2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BLNKB cell linker. (274 aa)
IRF8Interferon regulatory factor 8. (455 aa)
GFI1BGrowth factor independent 1B transcriptional repressor. (395 aa)
LMNB1Lamin B1; Belongs to the intermediate filament family. (609 aa)
EBF1EBF transcription factor 1. (591 aa)
IRF4Interferon regulatory factor 4. (451 aa)
IL7RInterleukin 7 receptor. (458 aa)
PAX5Paired box 5. (371 aa)
FOXO1Fork-head domain-containing protein. (613 aa)
SYKTyrosine-protein kinase. (630 aa)
SPIBETS domain-containing protein. (158 aa)
HPRT1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa)
IGHM-2Ig-like domain-containing protein. (167 aa)
RAG1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1128 aa)
RAG2V(D)J recombination-activating protein 2; Core component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T- cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. DNA cleavage by the RAG complex occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the pho [...] (527 aa)
IGHM-3Ig-like domain-containing protein. (167 aa)
CD19CD19 molecule. (573 aa)
IL7Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (175 aa)
CCND3Cyclin D3; Belongs to the cyclin family. (287 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (769 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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