STRINGSTRING
TXK TXK CD44 CD44 ANGPT1 ANGPT1 TNFRSF1A TNFRSF1A ENSOCUP00000044284 ENSOCUP00000044284 GAPDH GAPDH SRC SRC MPL MPL INSR INSR FGFR1 FGFR1 IL3RA IL3RA ABL1 ABL1 IL7 IL7 ENSOCUP00000037329 ENSOCUP00000037329 CD19 CD19 CD86 CD86 KIT KIT EPHB4 EPHB4 CSF1R CSF1R FGFR2 FGFR2 CD34 CD34 CXCR3 CXCR3 CSF3R CSF3R LOC103345451 LOC103345451 CD4 CD4 EPHA1 EPHA1 CSF2RA CSF2RA ROS1 ROS1 EPHA6 EPHA6 MERTK MERTK TNK1 TNK1 SPP1 SPP1 NGF NGF INS INS CXCR5 CXCR5 CCR7 CCR7 CSF2RB CSF2RB IL6 IL6 FLT1 FLT1 EPHA2 EPHA2 ACVRL1 ACVRL1 EDNRB EDNRB BMX BMX BMPR1A BMPR1A JAK2 JAK2 G1TC56_RABIT G1TC56_RABIT AXL AXL FYN FYN EPOR EPOR EPHA8 EPHA8 OSMR OSMR EPHB3 EPHB3 CCR8 CCR8 DDR2 DDR2 IL7R IL7R BTK BTK EGFR EGFR EPHA3 EPHA3 OSM OSM HCK HCK NTRK2 NTRK2 CD80 CD80 MST1R MST1R TIE1 TIE1 FGR FGR IL1A IL1A TNK2 TNK2 NGFR NGFR EPHA4 EPHA4 JAK1 JAK1 TYRO3 TYRO3 ZAP70 ZAP70 KDR KDR FLT3 FLT3 LCK LCK CCR1 CCR1 CSF2 CSF2 LIFR LIFR MRC1 MRC1 LYN LYN ACVR1 ACVR1 PDGFRB PDGFRB FRK FRK EPHA7 EPHA7 PDGFRA PDGFRA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TXKTyrosine-protein kinase. (556 aa)
CD44CD44 molecule (Indian blood group). (761 aa)
ANGPT1Angiopoietin 1. (551 aa)
TNFRSF1ATNF receptor superfamily member 1A. (472 aa)
ENSOCUP00000044284TGFb_propeptide domain-containing protein. (260 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (333 aa)
SRCTyrosine-protein kinase. (589 aa)
MPLMPL proto-oncogene, thrombopoietin receptor. (635 aa)
INSRTyrosine-protein kinase receptor. (1377 aa)
FGFR1Fibroblast growth factor receptor. (823 aa)
IL3RAUncharacterized protein. (394 aa)
ABL1Tyrosine-protein kinase. (1118 aa)
IL7Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (175 aa)
ENSOCUP00000037329TGFb_propeptide domain-containing protein. (263 aa)
CD19CD19 molecule. (573 aa)
CD86T-lymphocyte activation antigen CD86; Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. (336 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (970 aa)
EPHB4EPH receptor B4. (1011 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (973 aa)
FGFR2Fibroblast growth factor receptor. (894 aa)
CD34CD34 molecule. (415 aa)
CXCR3C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (370 aa)
CSF3RColony stimulating factor 3 receptor. (1027 aa)
LOC103345451TGFb_propeptide domain-containing protein. (203 aa)
CD4T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (536 aa)
EPHA1EPH receptor A1. (948 aa)
CSF2RAFibronectin type-III domain-containing protein. (443 aa)
ROS1Tyrosine-protein kinase receptor. (2288 aa)
EPHA6EPH receptor A6. (1130 aa)
MERTKMER proto-oncogene, tyrosine kinase. (968 aa)
TNK1Tyrosine kinase non receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (667 aa)
SPP1Osteopontin; Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction; Belongs to the osteopontin family. (311 aa)
NGFNerve growth factor. (157 aa)
INSInsulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (164 aa)
CXCR5C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family. (374 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa)
CSF2RBColony stimulating factor 2 receptor beta common subunit. (868 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (241 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1479 aa)
EPHA2EPH receptor A2. (1031 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (327 aa)
EDNRBEndothelin receptor type B; Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). Belongs to the G-protein coupled receptor 1 family. Endothelin receptor subfamily. EDNRB sub-subfamily. (441 aa)
BMXTyrosine-protein kinase. (655 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
G1TC56_RABITTGFb_propeptide domain-containing protein. (168 aa)
AXLAXL receptor tyrosine kinase. (625 aa)
FYNTyrosine-protein kinase. (537 aa)
EPORErythropoietin receptor. (554 aa)
EPHA8EPH receptor A8. (973 aa)
OSMROncostatin M receptor. (1088 aa)
EPHB3EPH receptor B3. (1075 aa)
CCR8C-C motif chemokine receptor 8; Belongs to the G-protein coupled receptor 1 family. (355 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (848 aa)
IL7RInterleukin 7 receptor. (458 aa)
BTKTyrosine-protein kinase. (659 aa)
EGFRReceptor protein-tyrosine kinase. (1193 aa)
EPHA3EPH receptor A3. (984 aa)
OSMUncharacterized protein. (333 aa)
HCKTyrosine-protein kinase. (525 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
CD80T-lymphocyte activation antigen CD80; Involved in the costimulatory signal essential for T lymphocytes activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor. (299 aa)
MST1RMacrophage stimulating 1 receptor. (1392 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (732 aa)
FGRTyrosine-protein kinase. (527 aa)
IL1AInterleukin-1 alpha; Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. (267 aa)
TNK2Tyrosine kinase non receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (853 aa)
NGFRNerve growth factor receptor. (407 aa)
EPHA4EPH receptor A4. (986 aa)
JAK1Tyrosine-protein kinase. (1151 aa)
TYRO3TYRO3 protein tyrosine kinase. (860 aa)
ZAP70Tyrosine-protein kinase. (623 aa)
KDRUncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
FLT3Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (993 aa)
LCKTyrosine-protein kinase. (637 aa)
CCR1Chemokine receptor; Belongs to the G-protein coupled receptor 1 family. (351 aa)
CSF2Uncharacterized protein. (144 aa)
LIFRLIF receptor subunit alpha. (1091 aa)
MRC1Mannose receptor C-type 1. (1455 aa)
LYNTyrosine-protein kinase. (636 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1147 aa)
FRKFyn related Src family tyrosine kinase. (389 aa)
EPHA7EPH receptor A7. (998 aa)
PDGFRAProtein kinase domain-containing protein. (773 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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