(7 nodes) (2014) The effect of zinc and D-penicillamine in a stable human hepatoma ATP7B knockout cell line. network (Oryctolagus cuniculus)

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Your Input:
	MT1B	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (56 aa)
	LOC103350073	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (62 aa)
	ATP7A	ATPase copper transporting alpha. (1499 aa)
	MT4	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (62 aa)
	CP	Ceruloplasmin; Belongs to the multicopper oxidase family. (1098 aa)
	ATP7B	ATPase copper transporting beta. (1465 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (333 aa)

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP7A	ATP7B	ENSOCUP00000012171	ENSOCUP00000043559	ATPase copper transporting alpha.	ATPase copper transporting beta.	0.905
ATP7A	CP	ENSOCUP00000012171	ENSOCUP00000033302	ATPase copper transporting alpha.	Ceruloplasmin; Belongs to the multicopper oxidase family.	0.857
ATP7A	LOC103350073	ENSOCUP00000012171	ENSOCUP00000006271	ATPase copper transporting alpha.	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.728
ATP7A	MT1B	ENSOCUP00000012171	ENSOCUP00000047546	ATPase copper transporting alpha.	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.727
ATP7A	MT4	ENSOCUP00000012171	ENSOCUP00000014837	ATPase copper transporting alpha.	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.728
ATP7B	ATP7A	ENSOCUP00000043559	ENSOCUP00000012171	ATPase copper transporting beta.	ATPase copper transporting alpha.	0.905
ATP7B	CP	ENSOCUP00000043559	ENSOCUP00000033302	ATPase copper transporting beta.	Ceruloplasmin; Belongs to the multicopper oxidase family.	0.929
ATP7B	LOC103350073	ENSOCUP00000043559	ENSOCUP00000006271	ATPase copper transporting beta.	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.741
ATP7B	MT1B	ENSOCUP00000043559	ENSOCUP00000047546	ATPase copper transporting beta.	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.741
ATP7B	MT4	ENSOCUP00000043559	ENSOCUP00000014837	ATPase copper transporting beta.	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.741
CP	ATP7A	ENSOCUP00000033302	ENSOCUP00000012171	Ceruloplasmin; Belongs to the multicopper oxidase family.	ATPase copper transporting alpha.	0.857
CP	ATP7B	ENSOCUP00000033302	ENSOCUP00000043559	Ceruloplasmin; Belongs to the multicopper oxidase family.	ATPase copper transporting beta.	0.929
CP	GAPDH	ENSOCUP00000033302	ENSOCUP00000044112	Ceruloplasmin; Belongs to the multicopper oxidase family.	Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...]	0.421
CP	LOC103350073	ENSOCUP00000033302	ENSOCUP00000006271	Ceruloplasmin; Belongs to the multicopper oxidase family.	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.539
CP	MT1B	ENSOCUP00000033302	ENSOCUP00000047546	Ceruloplasmin; Belongs to the multicopper oxidase family.	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.437
CP	MT4	ENSOCUP00000033302	ENSOCUP00000014837	Ceruloplasmin; Belongs to the multicopper oxidase family.	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.697
GAPDH	CP	ENSOCUP00000044112	ENSOCUP00000033302	Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...]	Ceruloplasmin; Belongs to the multicopper oxidase family.	0.421
GAPDH	LOC103350073	ENSOCUP00000044112	ENSOCUP00000006271	Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...]	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.411
GAPDH	MT1B	ENSOCUP00000044112	ENSOCUP00000047546	Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...]	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.426
GAPDH	MT4	ENSOCUP00000044112	ENSOCUP00000014837	Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...]	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.408