STRINGSTRING
IL7 IL7 IRF8 IRF8 CCR1 CCR1 IL7R IL7R PAX5 PAX5 IGLL1 IGLL1 IGHM-2 IGHM-2 CEBPA CEBPA GATA1 GATA1 IGHM-3 IGHM-3 CD4 CD4 IGHM IGHM CD34 CD34 KIT KIT CD19 CD19
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL7Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (175 aa)
IRF8Interferon regulatory factor 8. (455 aa)
CCR1Chemokine receptor; Belongs to the G-protein coupled receptor 1 family. (351 aa)
IL7RInterleukin 7 receptor. (458 aa)
PAX5Paired box 5. (371 aa)
IGLL1Lambda5. (208 aa)
IGHM-2Ig-like domain-containing protein. (167 aa)
CEBPACCAAT enhancer binding protein alpha. (402 aa)
GATA1GATA binding protein 1. (413 aa)
IGHM-3Ig-like domain-containing protein. (167 aa)
CD4T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (536 aa)
IGHMIg mu chain C region membrane-bound form. (548 aa)
CD34CD34 molecule. (415 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (970 aa)
CD19CD19 molecule. (573 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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