16 items (Oryctolagus cuniculus) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Predicted Interactions

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Your Input:
	CD19	CD19 molecule. (573 aa)
	CD40LG	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa)
	BACH2	BTB domain and CNC homolog 2. (774 aa)
	PXDNL	Peroxidasin like. (1467 aa)
	IRF4	Interferon regulatory factor 4. (451 aa)
	PAX5	Paired box 5. (371 aa)
	MYC	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (438 aa)
	RAG1	V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1128 aa)
	FOS	Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
	PXDN	Peroxidasin. (1411 aa)
	CD5	Uncharacterized protein. (488 aa)
	IL4	Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (144 aa)
	CD4	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (536 aa)
	CD40	Uncharacterized protein. (494 aa)
	BCL2	BH4_2 domain-containing protein. (389 aa)
	BCL6	BCL6 transcription repressor. (723 aa)

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BACH2	BCL6	ENSOCUP00000003659	ENSOCUP00000045134	BTB domain and CNC homolog 2.	BCL6 transcription repressor.	0.781
BACH2	CD19	ENSOCUP00000003659	ENSOCUP00000036537	BTB domain and CNC homolog 2.	CD19 molecule.	0.420
BACH2	CD4	ENSOCUP00000003659	ENSOCUP00000030708	BTB domain and CNC homolog 2.	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.452
BACH2	CD40	ENSOCUP00000003659	ENSOCUP00000034264	BTB domain and CNC homolog 2.	Uncharacterized protein.	0.531
BACH2	CD40LG	ENSOCUP00000003659	ENSOCUP00000003395	BTB domain and CNC homolog 2.	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	0.593
BACH2	IRF4	ENSOCUP00000003659	ENSOCUP00000008085	BTB domain and CNC homolog 2.	Interferon regulatory factor 4.	0.744
BACH2	PAX5	ENSOCUP00000003659	ENSOCUP00000010574	BTB domain and CNC homolog 2.	Paired box 5.	0.763
BCL2	BCL6	ENSOCUP00000036189	ENSOCUP00000045134	BH4_2 domain-containing protein.	BCL6 transcription repressor.	0.796
BCL2	CD19	ENSOCUP00000036189	ENSOCUP00000036537	BH4_2 domain-containing protein.	CD19 molecule.	0.679
BCL2	CD4	ENSOCUP00000036189	ENSOCUP00000030708	BH4_2 domain-containing protein.	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.781
BCL2	CD40	ENSOCUP00000036189	ENSOCUP00000034264	BH4_2 domain-containing protein.	Uncharacterized protein.	0.630
BCL2	CD40LG	ENSOCUP00000036189	ENSOCUP00000003395	BH4_2 domain-containing protein.	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	0.495
BCL2	CD5	ENSOCUP00000036189	ENSOCUP00000023266	BH4_2 domain-containing protein.	Uncharacterized protein.	0.719
BCL2	FOS	ENSOCUP00000036189	ENSOCUP00000021434	BH4_2 domain-containing protein.	Fos proto-oncogene, AP-1 transcription factor subunit.	0.580
BCL2	IL4	ENSOCUP00000036189	ENSOCUP00000025135	BH4_2 domain-containing protein.	Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...]	0.653
BCL2	IRF4	ENSOCUP00000036189	ENSOCUP00000008085	BH4_2 domain-containing protein.	Interferon regulatory factor 4.	0.523
BCL2	MYC	ENSOCUP00000036189	ENSOCUP00000012281	BH4_2 domain-containing protein.	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.	0.894
BCL2	PAX5	ENSOCUP00000036189	ENSOCUP00000010574	BH4_2 domain-containing protein.	Paired box 5.	0.541
BCL2	PXDN	ENSOCUP00000036189	ENSOCUP00000022906	BH4_2 domain-containing protein.	Peroxidasin.	0.911
BCL2	PXDNL	ENSOCUP00000036189	ENSOCUP00000004823	BH4_2 domain-containing protein.	Peroxidasin like.	0.911