STRINGSTRING
CD19 CD19 BLNK BLNK LYN LYN PXDNL PXDNL ZAP70 ZAP70 NFATC1 NFATC1 NCK1 NCK1 FGR FGR EBF1 EBF1 IRF4 IRF4 HCK HCK BTK BTK STAT3 STAT3 MYB MYB PAX5 PAX5 FOXO1 FOXO1 FYN FYN SYK SYK RAG1 RAG1 RAG2 RAG2 PXDN PXDN NCK2 NCK2 IL7 IL7 STAT1 STAT1 FOXO4 FOXO4 SRC SRC GAPDH GAPDH LEF1 LEF1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CD19CD19 molecule. (573 aa)
BLNKB cell linker. (274 aa)
LYNTyrosine-protein kinase. (636 aa)
PXDNLPeroxidasin like. (1467 aa)
ZAP70Tyrosine-protein kinase. (623 aa)
NFATC1RHD domain-containing protein. (672 aa)
NCK1Cytoplasmic protein. (377 aa)
FGRTyrosine-protein kinase. (527 aa)
EBF1EBF transcription factor 1. (591 aa)
IRF4Interferon regulatory factor 4. (451 aa)
HCKTyrosine-protein kinase. (525 aa)
BTKTyrosine-protein kinase. (659 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
MYBMYB proto-oncogene, transcription factor. (758 aa)
PAX5Paired box 5. (371 aa)
FOXO1Fork-head domain-containing protein. (613 aa)
FYNTyrosine-protein kinase. (537 aa)
SYKTyrosine-protein kinase. (630 aa)
RAG1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1128 aa)
RAG2V(D)J recombination-activating protein 2; Core component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T- cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. DNA cleavage by the RAG complex occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the pho [...] (527 aa)
PXDNPeroxidasin. (1411 aa)
NCK2Cytoplasmic protein. (380 aa)
IL7Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (175 aa)
STAT1Signal transducer and activator of transcription. (879 aa)
FOXO4Forkhead box O4. (503 aa)
SRCTyrosine-protein kinase. (589 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (333 aa)
LEF1Lymphoid enhancer binding factor 1. (414 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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