STRINGSTRING
H1-1 H1-1 GNA12 GNA12 MCM4 MCM4 BLNK BLNK CD83 CD83 CD74 CD74 FLT3 FLT3 APEX1 APEX1 KMT2D KMT2D TET2 TET2 KLHL6 KLHL6 GNA13 GNA13 EBF1 EBF1 IRF4 IRF4 SMAD2 SMAD2 EP300 EP300 PAX5 PAX5 RHOA RHOA EXO1 EXO1 IL6 IL6 HPRT1 HPRT1 IGHM-2 IGHM-2 IGHM-3 IGHM-3 CD4 CD4 CD34 CD34 CTNNB1 CTNNB1 CD79B CD79B MYD88 MYD88 KIT KIT BCL2 BCL2 CD19 CD19 MME MME BCL6 BCL6 MCM10 MCM10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H1-1Histone cluster 1 H1 family member a. (219 aa)
GNA12G protein subunit alpha 12. (457 aa)
MCM4DNA helicase; Belongs to the MCM family. (864 aa)
BLNKB cell linker. (274 aa)
CD83CD83 molecule. (292 aa)
CD74CD74 molecule. (375 aa)
FLT3Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (993 aa)
APEX1DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (318 aa)
KMT2DLysine methyltransferase 2D. (5446 aa)
TET2Tet methylcytosine dioxygenase 2. (2011 aa)
KLHL6Kelch like family member 6. (622 aa)
GNA13G protein subunit alpha 13. (377 aa)
EBF1EBF transcription factor 1. (591 aa)
IRF4Interferon regulatory factor 4. (451 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
EP300E1A binding protein p300. (2418 aa)
PAX5Paired box 5. (371 aa)
RHOARas homolog family member A. (193 aa)
EXO1Exonuclease 1. (831 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (241 aa)
HPRT1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa)
IGHM-2Ig-like domain-containing protein. (167 aa)
IGHM-3Ig-like domain-containing protein. (167 aa)
CD4T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (536 aa)
CD34CD34 molecule. (415 aa)
CTNNB1Catenin beta 1. (741 aa)
CD79BCD79b molecule. (282 aa)
MYD88Uncharacterized protein. (476 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (970 aa)
BCL2BH4_2 domain-containing protein. (389 aa)
CD19CD19 molecule. (573 aa)
MMENeprilysin; Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers. Belongs to the peptidase M13 family. (750 aa)
BCL6BCL6 transcription repressor. (723 aa)
MCM10Minichromosome maintenance 10 replication initiation factor. (881 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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