STRINGSTRING
PXDN PXDN SMAD4 SMAD4 PXDNL PXDNL ATP10A ATP10A PREB PREB EBF1 EBF1 IRF4 IRF4 PAX5 PAX5 IKZF1 IKZF1 ETV6 ETV6 LOC100340625 LOC100340625 CD34 CD34 CD19 CD19 MME MME NR3C1 NR3C1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PXDNPeroxidasin. (1411 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
PXDNLPeroxidasin like. (1467 aa)
ATP10APhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1506 aa)
PREBProlactin regulatory element binding. (418 aa)
EBF1EBF transcription factor 1. (591 aa)
IRF4Interferon regulatory factor 4. (451 aa)
PAX5Paired box 5. (371 aa)
IKZF1IKAROS family zinc finger 1. (515 aa)
ETV6ETS variant 6. (508 aa)
LOC100340625ANK_REP_REGION domain-containing protein. (324 aa)
CD34CD34 molecule. (415 aa)
CD19CD19 molecule. (573 aa)
MMENeprilysin; Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers. Belongs to the peptidase M13 family. (750 aa)
NR3C1Glucocorticoid receptor; Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Involved in chromatin remodeling. Plays a role in rapid mRNA degradation by binding to the 5' UTR of target mRNAs and interacting with PNRC2 in a ligand-dependent manner which recruits the RNA helicase UPF1 and the mRNA-decapping enzyme DCP [...] (773 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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