14 items (Oryctolagus cuniculus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Your Input:
	DCN	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (360 aa)
	FGF2	Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family. (155 aa)
	CCN2	Cellular communication network factor 2. (437 aa)
	TGFB2	Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
	EGR1	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (700 aa)
	THBS4	Thrombospondin 4. (997 aa)
	MKX	Mohawk homeobox. (357 aa)
	TNMD	Myodulin. (317 aa)
	G1TC56_RABIT	TGFb_propeptide domain-containing protein. (168 aa)
	POU5F1	POU domain protein. (360 aa)
	NANOG	Homeobox domain-containing protein. (306 aa)
	LOC103345451	TGFb_propeptide domain-containing protein. (203 aa)
	ENSOCUP00000037329	TGFb_propeptide domain-containing protein. (263 aa)
	ENSOCUP00000044284	TGFb_propeptide domain-containing protein. (260 aa)

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCN2	DCN	ENSOCUP00000002454	ENSOCUP00000006027	Cellular communication network factor 2.	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	0.808
CCN2	EGR1	ENSOCUP00000002454	ENSOCUP00000007289	Cellular communication network factor 2.	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.	0.531
CCN2	ENSOCUP00000037329	ENSOCUP00000002454	ENSOCUP00000037329	Cellular communication network factor 2.	TGFb_propeptide domain-containing protein.	0.858
CCN2	ENSOCUP00000044284	ENSOCUP00000002454	ENSOCUP00000044284	Cellular communication network factor 2.	TGFb_propeptide domain-containing protein.	0.858
CCN2	FGF2	ENSOCUP00000002454	ENSOCUP00000000416	Cellular communication network factor 2.	Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family.	0.706
CCN2	G1TC56_RABIT	ENSOCUP00000002454	ENSOCUP00000014344	Cellular communication network factor 2.	TGFb_propeptide domain-containing protein.	0.841
CCN2	LOC103345451	ENSOCUP00000002454	ENSOCUP00000031740	Cellular communication network factor 2.	TGFb_propeptide domain-containing protein.	0.858
CCN2	TGFB2	ENSOCUP00000002454	ENSOCUP00000004578	Cellular communication network factor 2.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.615
CCN2	TNMD	ENSOCUP00000002454	ENSOCUP00000009616	Cellular communication network factor 2.	Myodulin.	0.580
DCN	CCN2	ENSOCUP00000006027	ENSOCUP00000002454	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Cellular communication network factor 2.	0.808
DCN	ENSOCUP00000037329	ENSOCUP00000006027	ENSOCUP00000037329	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	TGFb_propeptide domain-containing protein.	0.984
DCN	ENSOCUP00000044284	ENSOCUP00000006027	ENSOCUP00000044284	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	TGFb_propeptide domain-containing protein.	0.984
DCN	FGF2	ENSOCUP00000006027	ENSOCUP00000000416	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family.	0.713
DCN	G1TC56_RABIT	ENSOCUP00000006027	ENSOCUP00000014344	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	TGFb_propeptide domain-containing protein.	0.975
DCN	LOC103345451	ENSOCUP00000006027	ENSOCUP00000031740	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	TGFb_propeptide domain-containing protein.	0.984
DCN	MKX	ENSOCUP00000006027	ENSOCUP00000009176	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Mohawk homeobox.	0.731
DCN	TGFB2	ENSOCUP00000006027	ENSOCUP00000004578	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.963
DCN	THBS4	ENSOCUP00000006027	ENSOCUP00000007987	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Thrombospondin 4.	0.629
DCN	TNMD	ENSOCUP00000006027	ENSOCUP00000009616	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Myodulin.	0.867
EGR1	CCN2	ENSOCUP00000007289	ENSOCUP00000002454	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.	Cellular communication network factor 2.	0.531