STRINGSTRING
MX1 MX1 CEBPB CEBPB IGLL1 IGLL1 EPOR EPOR HDAC9 HDAC9 FOXO1 FOXO1 CALML5 CALML5 POU2AF1 POU2AF1 CALM1 CALM1 MYB MYB MYOG MYOG KLF7 KLF7 EBF1 EBF1 HDAC5 HDAC5 BACH2 BACH2 CALM2 CALM2 MEF2C MEF2C GAPDH GAPDH MPO MPO JUN JUN IL7 IL7 CD19 CD19 KIT KIT CSF1R CSF1R CAMK2D CAMK2D CSF3R CSF3R CXCL9 CXCL9 ETS1 ETS1 VPREB1-2 VPREB1-2 G1TYG1_RABIT G1TYG1_RABIT CEBPA CEBPA RAG1 RAG1 VPREB1 VPREB1 G1TJG6_RABIT G1TJG6_RABIT
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MX1Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (697 aa)
CEBPBCCAAT enhancer binding protein beta. (353 aa)
IGLL1Lambda5. (208 aa)
EPORErythropoietin receptor. (554 aa)
HDAC9Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1068 aa)
FOXO1Fork-head domain-containing protein. (613 aa)
CALML5Calmodulin like 5. (149 aa)
POU2AF1POU class 2 homeobox associating factor 1. (266 aa)
CALM1Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). (149 aa)
MYBMYB proto-oncogene, transcription factor. (758 aa)
MYOGMyogenin. (225 aa)
KLF7Kruppel like factor 7. (302 aa)
EBF1EBF transcription factor 1. (591 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1115 aa)
BACH2BTB domain and CNC homolog 2. (774 aa)
CALM2Uncharacterized protein; Belongs to the calmodulin family. (153 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (333 aa)
MPOMyeloperoxidase. (725 aa)
JUNBZIP domain-containing protein; Belongs to the bZIP family. (352 aa)
IL7Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (175 aa)
CD19CD19 molecule. (573 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (970 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (973 aa)
CAMK2DCalcium/calmodulin-dependent protein kinase type II subunit delta; Calcium/calmodulin-dependent protein kinase involved in the regulation of Ca(2+) homeostatis and excitation-contraction coupling (ECC) in heart by targeting ion channels, transporters and accessory proteins involved in Ca(2+) influx into the myocyte, Ca(2+) release from the sarcoplasmic reticulum (SR), SR Ca(2+) uptake and Na(+) and K(+) channel transport. Targets also transcription factors and signaling molecules to regulate heart function. In its activated form, is involved in the pathogenesis of dilated cardiomyopath [...] (505 aa)
CSF3RColony stimulating factor 3 receptor. (1027 aa)
CXCL9C-X-C motif chemokine. (153 aa)
ETS1Uncharacterized protein. (533 aa)
VPREB1-2Ig-like domain-containing protein. (147 aa)
G1TYG1_RABITGlyceraldehyde-3-phosphate dehydrogenase. (369 aa)
CEBPACCAAT enhancer binding protein alpha. (402 aa)
RAG1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1128 aa)
VPREB1Ig-like domain-containing protein. (147 aa)
G1TJG6_RABITGlyceraldehyde-3-phosphate dehydrogenase. (305 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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