STRINGSTRING
GAPDH GAPDH ENSOCUP00000044284 ENSOCUP00000044284 MPO MPO ENSOCUP00000037329 ENSOCUP00000037329 LOC103345451 LOC103345451 SMAD3 SMAD3 IL1B IL1B G1TC56_RABIT G1TC56_RABIT COL1A1 COL1A1 SMAD2 SMAD2 CD68 CD68 FST FST
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GAPDHGlyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (333 aa)
ENSOCUP00000044284TGFb_propeptide domain-containing protein. (260 aa)
MPOMyeloperoxidase. (725 aa)
ENSOCUP00000037329TGFb_propeptide domain-containing protein. (263 aa)
LOC103345451TGFb_propeptide domain-containing protein. (203 aa)
SMAD3SMAD family member 3. (230 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (234 aa)
G1TC56_RABITTGFb_propeptide domain-containing protein. (168 aa)
COL1A1Collagen alpha-1(I) chain. (1348 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
CD68CD68 molecule. (334 aa)
FSTFollistatin. (310 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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