9 items (Oryctolagus cuniculus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Your Input:
	SMAD2	Mothers against decapentaplegic homolog. (467 aa)
	G1TC56_RABIT	TGFb_propeptide domain-containing protein. (168 aa)
	IGF1	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (195 aa)
	BMP7	TGF_BETA_2 domain-containing protein. (170 aa)
	LOC103345451	TGFb_propeptide domain-containing protein. (203 aa)
	ENSOCUP00000037329	TGFb_propeptide domain-containing protein. (263 aa)
	ENSOCUP00000044284	TGFb_propeptide domain-containing protein. (260 aa)
	FGF2	Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family. (155 aa)
	TGFB3	Transforming growth factor beta 3. (458 aa)

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP7	ENSOCUP00000037329	ENSOCUP00000022037	ENSOCUP00000037329	TGF_BETA_2 domain-containing protein.	TGFb_propeptide domain-containing protein.	0.566
BMP7	ENSOCUP00000044284	ENSOCUP00000022037	ENSOCUP00000044284	TGF_BETA_2 domain-containing protein.	TGFb_propeptide domain-containing protein.	0.566
BMP7	FGF2	ENSOCUP00000022037	ENSOCUP00000000416	TGF_BETA_2 domain-containing protein.	Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family.	0.756
BMP7	G1TC56_RABIT	ENSOCUP00000022037	ENSOCUP00000014344	TGF_BETA_2 domain-containing protein.	TGFb_propeptide domain-containing protein.	0.540
BMP7	IGF1	ENSOCUP00000022037	ENSOCUP00000021389	TGF_BETA_2 domain-containing protein.	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	0.729
BMP7	LOC103345451	ENSOCUP00000022037	ENSOCUP00000031740	TGF_BETA_2 domain-containing protein.	TGFb_propeptide domain-containing protein.	0.566
BMP7	SMAD2	ENSOCUP00000022037	ENSOCUP00000009717	TGF_BETA_2 domain-containing protein.	Mothers against decapentaplegic homolog.	0.834
ENSOCUP00000037329	BMP7	ENSOCUP00000037329	ENSOCUP00000022037	TGFb_propeptide domain-containing protein.	TGF_BETA_2 domain-containing protein.	0.566
ENSOCUP00000037329	ENSOCUP00000044284	ENSOCUP00000037329	ENSOCUP00000044284	TGFb_propeptide domain-containing protein.	TGFb_propeptide domain-containing protein.	0.412
ENSOCUP00000037329	FGF2	ENSOCUP00000037329	ENSOCUP00000000416	TGFb_propeptide domain-containing protein.	Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family.	0.820
ENSOCUP00000037329	G1TC56_RABIT	ENSOCUP00000037329	ENSOCUP00000014344	TGFb_propeptide domain-containing protein.	TGFb_propeptide domain-containing protein.	0.429
ENSOCUP00000037329	IGF1	ENSOCUP00000037329	ENSOCUP00000021389	TGFb_propeptide domain-containing protein.	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	0.860
ENSOCUP00000037329	LOC103345451	ENSOCUP00000037329	ENSOCUP00000031740	TGFb_propeptide domain-containing protein.	TGFb_propeptide domain-containing protein.	0.419
ENSOCUP00000037329	SMAD2	ENSOCUP00000037329	ENSOCUP00000009717	TGFb_propeptide domain-containing protein.	Mothers against decapentaplegic homolog.	0.894
ENSOCUP00000037329	TGFB3	ENSOCUP00000037329	ENSOCUP00000009817	TGFb_propeptide domain-containing protein.	Transforming growth factor beta 3.	0.482
ENSOCUP00000044284	BMP7	ENSOCUP00000044284	ENSOCUP00000022037	TGFb_propeptide domain-containing protein.	TGF_BETA_2 domain-containing protein.	0.566
ENSOCUP00000044284	ENSOCUP00000037329	ENSOCUP00000044284	ENSOCUP00000037329	TGFb_propeptide domain-containing protein.	TGFb_propeptide domain-containing protein.	0.412
ENSOCUP00000044284	FGF2	ENSOCUP00000044284	ENSOCUP00000000416	TGFb_propeptide domain-containing protein.	Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family.	0.820
ENSOCUP00000044284	G1TC56_RABIT	ENSOCUP00000044284	ENSOCUP00000014344	TGFb_propeptide domain-containing protein.	TGFb_propeptide domain-containing protein.	0.543
ENSOCUP00000044284	IGF1	ENSOCUP00000044284	ENSOCUP00000021389	TGFb_propeptide domain-containing protein.	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	0.860