STRINGSTRING
DCUN1D2 DCUN1D2 CUL1 CUL1 NEDD8 NEDD8 CKMT1A CKMT1A CAND1 CAND1 DCUN1D5 DCUN1D5 UBA3 UBA3 SKP2 SKP2 CKMT2 CKMT2 DCUN1D4 DCUN1D4 DCUN1D1 DCUN1D1 MYC MYC CCNA1 CCNA1 UBE2M UBE2M DCUN1D3 DCUN1D3 CCNA2 CCNA2 SKP1 SKP1 UBE2F UBE2F CDK2 CDK2 CKB CKB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DCUN1D2DCN1-like protein. (250 aa)
CUL1Cullin 1; Belongs to the cullin family. (775 aa)
NEDD8NEDD8; Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins (By similarity). (81 aa)
CKMT1ACreatine kinase, mitochondrial 1A (Predicted); Belongs to the ATP:guanido phosphotransferase family. (417 aa)
CAND1Cullin associated and neddylation dissociated 1. (1207 aa)
DCUN1D5DCN1-like protein. (237 aa)
UBA3Ubiquitin like modifier activating enzyme 3. (463 aa)
SKP2F-box domain-containing protein. (435 aa)
CKMT2Creatine kinase S-type, mitochondrial; Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa (By similarity). (419 aa)
DCUN1D4DCN1-like protein. (285 aa)
DCUN1D1DCN1-like protein. (345 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (438 aa)
CCNA1Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (423 aa)
UBE2MUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (457 aa)
DCUN1D3DCN1-like protein. (304 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (424 aa)
SKP1Uncharacterized protein; Belongs to the SKP1 family. (163 aa)
UBE2FUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (220 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa)
CKBCreatine kinase B-type; Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa; Belongs to the ATP:guanido phosphotransferase family. (425 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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