STRINGSTRING
FST FST DCN DCN FN1 FN1 SPARC SPARC RHOA RHOA G1TC56_RABIT G1TC56_RABIT VTN VTN LOC103345451 LOC103345451 PXN PXN ENSOCUP00000037329 ENSOCUP00000037329 TGFBI TGFBI ENSOCUP00000044284 ENSOCUP00000044284 ILK ILK CASP8 CASP8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FSTFollistatin. (310 aa)
DCNDecorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (360 aa)
FN1Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity). (2427 aa)
SPARCSPARC; Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity (By similarity); Belongs to the SPARC family. (315 aa)
RHOARas homolog family member A. (193 aa)
G1TC56_RABITTGFb_propeptide domain-containing protein. (168 aa)
VTNVitronectin; Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway. (475 aa)
LOC103345451TGFb_propeptide domain-containing protein. (203 aa)
PXNPaxillin. (1072 aa)
ENSOCUP00000037329TGFb_propeptide domain-containing protein. (263 aa)
TGFBITransforming growth factor-beta-induced protein ig-h3; Plays a role in cell adhesion (By similarity). May play a role in cell-collagen interactions (By similarity). (701 aa)
ENSOCUP00000044284TGFb_propeptide domain-containing protein. (260 aa)
ILKIntegrin linked kinase. (510 aa)
CASP8DED domain-containing protein. (109 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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