Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AR | DAXX | ENSOCUP00000042647 | ENSOCUP00000009116 | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | Death domain associated protein. | 0.567 |
| AR | MYC | ENSOCUP00000042647 | ENSOCUP00000012281 | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. | 0.712 |
| AR | PTEN | ENSOCUP00000042647 | ENSOCUP00000007574 | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. | 0.824 |
| AR | PXDN | ENSOCUP00000042647 | ENSOCUP00000022906 | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | Peroxidasin. | 0.731 |
| AR | PXDNL | ENSOCUP00000042647 | ENSOCUP00000004823 | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | Peroxidasin like. | 0.731 |
| AR | SPOP | ENSOCUP00000042647 | ENSOCUP00000031428 | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | Speckle type BTB/POZ protein. | 0.869 |
| AR | TRIM24 | ENSOCUP00000042647 | ENSOCUP00000032746 | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | Tripartite motif containing 24. | 0.553 |
| AR | VCL | ENSOCUP00000042647 | ENSOCUP00000039299 | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | Vinculin. | 0.400 |
| CUL1 | CUL2 | ENSOCUP00000002198 | ENSOCUP00000012675 | Cullin 1; Belongs to the cullin family. | Cullin 2; Belongs to the cullin family. | 0.742 |
| CUL1 | CUL3 | ENSOCUP00000002198 | ENSOCUP00000031324 | Cullin 1; Belongs to the cullin family. | Cullin 3; Belongs to the cullin family. | 0.887 |
| CUL1 | CUL4A | ENSOCUP00000002198 | ENSOCUP00000008283 | Cullin 1; Belongs to the cullin family. | Cullin 4A; Belongs to the cullin family. | 0.903 |
| CUL1 | CUL4B | ENSOCUP00000002198 | ENSOCUP00000040452 | Cullin 1; Belongs to the cullin family. | Cullin 4B; Belongs to the cullin family. | 0.845 |
| CUL1 | CUL5 | ENSOCUP00000002198 | ENSOCUP00000009389 | Cullin 1; Belongs to the cullin family. | Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...] | 0.865 |
| CUL1 | KEAP1 | ENSOCUP00000002198 | ENSOCUP00000044015 | Cullin 1; Belongs to the cullin family. | Kelch like ECH associated protein 1. | 0.858 |
| CUL1 | MYC | ENSOCUP00000002198 | ENSOCUP00000012281 | Cullin 1; Belongs to the cullin family. | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. | 0.855 |
| CUL1 | PLK1 | ENSOCUP00000002198 | ENSOCUP00000007325 | Cullin 1; Belongs to the cullin family. | Serine/threonine-protein kinase PLK. | 0.796 |
| CUL1 | PTEN | ENSOCUP00000002198 | ENSOCUP00000007574 | Cullin 1; Belongs to the cullin family. | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. | 0.404 |
| CUL1 | PXDN | ENSOCUP00000002198 | ENSOCUP00000022906 | Cullin 1; Belongs to the cullin family. | Peroxidasin. | 0.459 |
| CUL1 | PXDNL | ENSOCUP00000002198 | ENSOCUP00000004823 | Cullin 1; Belongs to the cullin family. | Peroxidasin like. | 0.455 |
| CUL1 | SKP1 | ENSOCUP00000002198 | ENSOCUP00000020468 | Cullin 1; Belongs to the cullin family. | Uncharacterized protein; Belongs to the SKP1 family. | 0.999 |
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