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BMP4 BMP4 SPARC SPARC G1TC56_RABIT G1TC56_RABIT G1TJG6_RABIT G1TJG6_RABIT G1TYG1_RABIT G1TYG1_RABIT FSTL1 FSTL1 LOC103345451 LOC103345451 ENSOCUP00000037329 ENSOCUP00000037329 ENSOCUP00000044284 ENSOCUP00000044284 GAPDH GAPDH NDRG1 NDRG1 FST FST DIP2A DIP2A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BMP4Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity). (409 aa)
SPARCSPARC; Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity (By similarity); Belongs to the SPARC family. (315 aa)
G1TC56_RABITTGFb_propeptide domain-containing protein. (168 aa)
G1TJG6_RABITGlyceraldehyde-3-phosphate dehydrogenase. (305 aa)
G1TYG1_RABITGlyceraldehyde-3-phosphate dehydrogenase. (369 aa)
FSTL1Follistatin like 1. (425 aa)
LOC103345451TGFb_propeptide domain-containing protein. (203 aa)
ENSOCUP00000037329TGFb_propeptide domain-containing protein. (263 aa)
ENSOCUP00000044284TGFb_propeptide domain-containing protein. (260 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (333 aa)
NDRG1N-myc downstream regulated 1. (438 aa)
FSTFollistatin. (310 aa)
DIP2ADisco interacting protein 2 homolog A. (1432 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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