STRINGSTRING
TRIM63 TRIM63 MYL9 MYL9 MYF6 MYF6 CCN2 CCN2 MYH4 MYH4 CCN1 CCN1 MYH9 MYH9 PXDNL PXDNL ACTA2 ACTA2 KRT25 KRT25 MYOG MYOG MEF2D MEF2D COL1A1 COL1A1 PCOLCE2 PCOLCE2 ADAMTS1 ADAMTS1 B2M B2M MYH1 MYH1 P4HA2 P4HA2 BGLAP BGLAP PPIA PPIA HAS2 HAS2 PXDN PXDN MYH11 MYH11 MYL2 MYL2 BMP1 BMP1 PTN PTN TUBB1 TUBB1 P4HA3 P4HA3 MMP1 MMP1 MYL1 MYL1 MYH10 MYH10 FBXO32 FBXO32 MYLK2 MYLK2 GAPDH GAPDH ACTG1 ACTG1 P4HA1 P4HA1 NEB NEB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TRIM63Tripartite motif containing 63. (400 aa)
MYL9Myosin light chain 9. (172 aa)
MYF6Myogenic factor 6. (242 aa)
CCN2Cellular communication network factor 2. (437 aa)
MYH4Myosin-4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1939 aa)
CCN1Cellular communication network factor 1. (386 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1920 aa)
PXDNLPeroxidasin like. (1467 aa)
ACTA2Actin, aortic smooth muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. (471 aa)
KRT25Keratin 25; Belongs to the intermediate filament family. (450 aa)
MYOGMyogenin. (225 aa)
MEF2DMyocyte enhancer factor 2D. (517 aa)
COL1A1Collagen alpha-1(I) chain. (1348 aa)
PCOLCE2Procollagen C-endopeptidase enhancer 2. (417 aa)
ADAMTS1ADAM metallopeptidase with thrombospondin type 1 motif 1. (887 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (120 aa)
MYH1Myosin-4; Muscle contraction. (1938 aa)
P4HA2Prolyl 4-hydroxylase subunit alpha 2. (544 aa)
BGLAPOsteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. (100 aa)
PPIAPeptidyl-prolyl cis-trans isomerase A, N-terminally processed; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding; Belongs to the cyclophilin-type PPIase family. PPIase A subfamily. (164 aa)
HAS2Uncharacterized protein. (556 aa)
PXDNPeroxidasin. (1411 aa)
MYH11Myosin-11; Muscle contraction. (1944 aa)
MYL2Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; Contractile protein that plays a role in heart development and function (By similarity). Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin [...] (232 aa)
BMP1Metalloendopeptidase. (984 aa)
PTNPleiotrophin. (242 aa)
TUBB1Tubulin beta 1 class VI; Belongs to the tubulin family. (605 aa)
P4HA3Prolyl 4-hydroxylase subunit alpha 3. (525 aa)
MMP1Interstitial collagenase; Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X; Belongs to the peptidase M10A family. (475 aa)
MYL1Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. (193 aa)
MYH10Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2007 aa)
FBXO32F-box protein 32. (364 aa)
MYLK2Myosin light chain kinase 2, skeletal/cardiac muscle; Implicated in the level of global muscle contraction and cardiac function (By similarity). Phosphorylates a specific serine in the N-terminus of a myosin light chain. (608 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (333 aa)
ACTG1Actin gamma 1; Belongs to the actin family. (323 aa)
P4HA1Prolyl 4-hydroxylase subunit alpha 1. (534 aa)
NEBNebulin. (6666 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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