Your Input: | |||||
EZH1 | Enhancer of zeste 1 polycomb repressive complex 2 subunit. (834 aa) | ||||
PRDM1 | PR/SET domain 1. (889 aa) | ||||
BCR | BCR activator of RhoGEF and GTPase. (1192 aa) | ||||
GATA1 | GATA binding protein 1. (413 aa) | ||||
CD5 | Uncharacterized protein. (488 aa) | ||||
ASXL1 | ASXL transcriptional regulator 1. (1512 aa) | ||||
RAG1 | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1128 aa) | ||||
IL10 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (304 aa) | ||||
LDB1 | LIM domain binding 1. (410 aa) | ||||
HOXB5 | Homeobox B5. (269 aa) | ||||
GATA3 | GATA binding protein 3. (444 aa) | ||||
TCF12 | Transcription factor 12. (675 aa) | ||||
B2M | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (120 aa) | ||||
CD93 | CD93 molecule. (653 aa) | ||||
HDAC9 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1068 aa) | ||||
IKZF1 | IKAROS family zinc finger 1. (515 aa) | ||||
FOXO1 | Fork-head domain-containing protein. (613 aa) | ||||
CD48 | Ig-like domain-containing protein. (291 aa) | ||||
SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5. (1051 aa) | ||||
PAX5 | Paired box 5. (371 aa) | ||||
RUNX2 | RUNX family transcription factor 2. (343 aa) | ||||
FOXP3 | Forkhead box P3. (455 aa) | ||||
IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. (153 aa) | ||||
CD69 | CD69 molecule. (201 aa) | ||||
EBF1 | EBF transcription factor 1. (591 aa) | ||||
FOXP1 | Fork-head domain-containing protein. (714 aa) | ||||
NFATC1 | RHD domain-containing protein. (672 aa) | ||||
LMO2 | LIM domain only 2. (158 aa) | ||||
BCL11A | BAF chromatin remodeling complex subunit BCL11A. (975 aa) | ||||
CD44 | CD44 molecule (Indian blood group). (761 aa) | ||||
ACTB | Uncharacterized protein. (357 aa) | ||||
GAPDH | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (333 aa) | ||||
CBX8 | Chromobox 8. (434 aa) | ||||
IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (198 aa) | ||||
IL7 | Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (175 aa) | ||||
CD19 | CD19 molecule. (573 aa) | ||||
KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (970 aa) | ||||
CD4 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (536 aa) |