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CUL1 | Cullin 1; Belongs to the cullin family. (775 aa) | ||||
DDB2 | Damage specific DNA binding protein 2. (427 aa) | ||||
DDB1 | Damage specific DNA binding protein 1. (1140 aa) | ||||
CUL7 | Cullin 7; Belongs to the cullin family. (1728 aa) | ||||
GAPDH | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (333 aa) | ||||
CUL4B | Cullin 4B; Belongs to the cullin family. (901 aa) | ||||
STAT1 | Signal transducer and activator of transcription. (879 aa) | ||||
CUL3 | Cullin 3; Belongs to the cullin family. (771 aa) | ||||
PIK3C3 | Phosphatidylinositol 3-kinase catalytic subunit type 3. (899 aa) | ||||
SMUG1 | Single-strand-selective monofunctional uracil-DNA glycosylase 1. (277 aa) | ||||
SKP1 | Uncharacterized protein; Belongs to the SKP1 family. (163 aa) | ||||
CDT1 | Chromatin licensing and DNA replication factor 1. (365 aa) | ||||
CUL2 | Cullin 2; Belongs to the cullin family. (745 aa) | ||||
CUL5 | Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...] (780 aa) | ||||
DCAF1 | DDB1 and CUL4 associated factor 1. (1507 aa) | ||||
CUL4A | Cullin 4A; Belongs to the cullin family. (759 aa) | ||||
DCAF13 | DDB1 and CUL4 associated factor 13. (596 aa) | ||||
PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |