STRINGSTRING
GAS7 GAS7 TUBB TUBB DIPK1C DIPK1C ANKRD13D ANKRD13D CDH12 CDH12 EBF1 EBF1 IL7R IL7R UGT3A2 UGT3A2 PAX5 PAX5 RUNX1 RUNX1 IKZF1 IKZF1 ETV6 ETV6 GATA3 GATA3 TFEB TFEB IGHM-2 IGHM-2 SPRY4 SPRY4 YY1 YY1 SLC7A8 SLC7A8 RAG1 RAG1 RAG2 RAG2 ADGB ADGB IGHM-3 IGHM-3 ARID5B ARID5B BCL2 BCL2 IL7 IL7 ZNF148 ZNF148 MPO MPO
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GAS7Growth arrest specific 7. (466 aa)
TUBBTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
DIPK1CDivergent protein kinase domain 1C. (433 aa)
ANKRD13DUncharacterized protein. (257 aa)
CDH12Cadherin 12; Cadherins are calcium-dependent cell adhesion proteins. (794 aa)
EBF1EBF transcription factor 1. (591 aa)
IL7RInterleukin 7 receptor. (458 aa)
UGT3A2UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (523 aa)
PAX5Paired box 5. (371 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (466 aa)
IKZF1IKAROS family zinc finger 1. (515 aa)
ETV6ETS variant 6. (508 aa)
GATA3GATA binding protein 3. (444 aa)
TFEBBHLH domain-containing protein. (485 aa)
IGHM-2Ig-like domain-containing protein. (167 aa)
SPRY4Sprouty RTK signaling antagonist 4. (321 aa)
YY1Uncharacterized protein. (190 aa)
SLC7A8Large neutral amino acids transporter small subunit 2; Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (re)absorption of neutral amino acids. Involved in the uptake of methylmercury (MeHg) when administe [...] (535 aa)
RAG1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1128 aa)
RAG2V(D)J recombination-activating protein 2; Core component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T- cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. DNA cleavage by the RAG complex occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the pho [...] (527 aa)
ADGBAndroglobin; Belongs to the peptidase C2 family. (1634 aa)
IGHM-3Ig-like domain-containing protein. (167 aa)
ARID5BAT-rich interaction domain 5B. (1191 aa)
BCL2BH4_2 domain-containing protein. (389 aa)
IL7Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (175 aa)
ZNF148Zinc finger protein 148. (794 aa)
MPOMyeloperoxidase. (725 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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