STRINGSTRING
MEF2A MEF2A WNT5A WNT5A MYF6 MYF6 TGFB2 TGFB2 PAX7 PAX7 G1SV95_RABIT G1SV95_RABIT MSTN MSTN MAPK1 MAPK1 BMP7 BMP7 EIF5A EIF5A DLK1 DLK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MEF2AMyocyte enhancer factor 2A. (511 aa)
WNT5AProtein Wnt-5a; Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta- catenin-induced reporter gene expression (By similarity). Suppression of the canonical pathway allows chondrogenesis to occur. Inhibits tumor formation. Stimulates cell migration. Decrease [...] (380 aa)
MYF6Myogenic factor 6. (242 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
PAX7Paired box 7. (476 aa)
G1SV95_RABITTransforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
MSTNMyostatin. (375 aa)
MAPK1Mitogen-activated protein kinase. (364 aa)
BMP7TGF_BETA_2 domain-containing protein. (170 aa)
EIF5AEukaryotic translation initiation factor 5A-1; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an import [...] (154 aa)
DLK1Delta like non-canonical Notch ligand 1. (497 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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