STRINGSTRING
NEDD8 NEDD8 PCNT PCNT GLB1 GLB1 DCUN1D5 DCUN1D5 UBA3 UBA3 GLB1L3 GLB1L3 COPS5 COPS5 DCUN1D4 DCUN1D4 MEI1 MEI1 LOC100357927 LOC100357927 H3F3B H3F3B ALB ALB H3C13 H3C13 LOC100345683 LOC100345683 H3-3A H3-3A LOC100344410 LOC100344410 G1TX56_RABIT G1TX56_RABIT G1TJR7_RABIT G1TJR7_RABIT CUL3 CUL3 KLHL13 KLHL13 ENSOCUP00000042583 ENSOCUP00000042583 DCUN1D2 DCUN1D2 GLB1L2 GLB1L2 LOC103345097 LOC103345097 CUL1 CUL1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NEDD8NEDD8; Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins (By similarity). (81 aa)
PCNTPericentrin. (3295 aa)
GLB1Beta-galactosidase. (843 aa)
DCUN1D5DCN1-like protein. (237 aa)
UBA3Ubiquitin like modifier activating enzyme 3. (463 aa)
GLB1L3Beta-galactosidase. (654 aa)
COPS5COP9 signalosome subunit 5. (334 aa)
DCUN1D4DCN1-like protein. (285 aa)
MEI1Meiotic double-stranded break formation protein 1. (1276 aa)
LOC100357927Histone domain-containing protein. (136 aa)
H3F3BHistone H3; Belongs to the histone H3 family. (136 aa)
ALBSerum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] (608 aa)
H3C13Histone H3; Belongs to the histone H3 family. (136 aa)
LOC100345683Histone H3; Belongs to the histone H3 family. (136 aa)
H3-3AHistone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...] (136 aa)
LOC100344410Histone domain-containing protein. (136 aa)
G1TX56_RABITHistone H3; Belongs to the histone H3 family. (136 aa)
G1TJR7_RABITHistone H3; Belongs to the histone H3 family. (136 aa)
CUL3Cullin 3; Belongs to the cullin family. (771 aa)
KLHL13Kelch like family member 13. (658 aa)
ENSOCUP00000042583Histone H3; Belongs to the histone H3 family. (115 aa)
DCUN1D2DCN1-like protein. (250 aa)
GLB1L2Beta-galactosidase. (699 aa)
LOC103345097Beta-galactosidase. (683 aa)
CUL1Cullin 1; Belongs to the cullin family. (775 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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