node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BDNF | FGF2 | ENSOCUP00000036666 | ENSOCUP00000000416 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family. | 0.863 |
BDNF | FMR1 | ENSOCUP00000036666 | ENSOCUP00000012576 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | Fragile X mental retardation 1. | 0.580 |
BDNF | GAD1 | ENSOCUP00000036666 | ENSOCUP00000035362 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | Glutamate decarboxylase 1. | 0.544 |
BDNF | GAPDH | ENSOCUP00000036666 | ENSOCUP00000044112 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] | 0.841 |
BDNF | NLGN1 | ENSOCUP00000036666 | ENSOCUP00000044921 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | Neuroligin 1. | 0.463 |
BDNF | NRXN1 | ENSOCUP00000036666 | ENSOCUP00000034839 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | Neurexin 1. | 0.500 |
DLX5 | GAD1 | ENSOCUP00000037071 | ENSOCUP00000035362 | Distal-less homeobox 5. | Glutamate decarboxylase 1. | 0.565 |
ELAVL1 | FMR1 | ENSOCUP00000013630 | ENSOCUP00000012576 | ELAV-like protein; Belongs to the RRM elav family. | Fragile X mental retardation 1. | 0.593 |
ELAVL1 | RBFOX1 | ENSOCUP00000013630 | ENSOCUP00000001045 | ELAV-like protein; Belongs to the RRM elav family. | RNA binding protein fox-1 homolog 1; RNA-binding protein that regulates alternative splicing events. | 0.612 |
FAM49B | LRRC40 | ENSOCUP00000011784 | ENSOCUP00000001722 | Family with sequence similarity 49 member B. | Leucine rich repeat containing 40. | 0.587 |
FAM49B | RPL22 | ENSOCUP00000011784 | ENSOCUP00000019977 | Family with sequence similarity 49 member B. | Uncharacterized protein. | 0.447 |
FAM49B | TEX2 | ENSOCUP00000011784 | ENSOCUP00000036784 | Family with sequence similarity 49 member B. | Testis expressed 2. | 0.661 |
FGF2 | BDNF | ENSOCUP00000000416 | ENSOCUP00000036666 | Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family. | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | 0.863 |
FGF2 | GAPDH | ENSOCUP00000000416 | ENSOCUP00000044112 | Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family. | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] | 0.852 |
FMR1 | BDNF | ENSOCUP00000012576 | ENSOCUP00000036666 | Fragile X mental retardation 1. | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | 0.580 |
FMR1 | ELAVL1 | ENSOCUP00000012576 | ENSOCUP00000013630 | Fragile X mental retardation 1. | ELAV-like protein; Belongs to the RRM elav family. | 0.593 |
FMR1 | GAPDH | ENSOCUP00000012576 | ENSOCUP00000044112 | Fragile X mental retardation 1. | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] | 0.481 |
FMR1 | NLGN1 | ENSOCUP00000012576 | ENSOCUP00000044921 | Fragile X mental retardation 1. | Neuroligin 1. | 0.576 |
FMR1 | NRXN1 | ENSOCUP00000012576 | ENSOCUP00000034839 | Fragile X mental retardation 1. | Neurexin 1. | 0.583 |
FMR1 | RBFOX1 | ENSOCUP00000012576 | ENSOCUP00000001045 | Fragile X mental retardation 1. | RNA binding protein fox-1 homolog 1; RNA-binding protein that regulates alternative splicing events. | 0.426 |