STRINGSTRING
FGF2 FGF2 RBFOX1 RBFOX1 LRRC40 LRRC40 RAB23 RAB23 GNB1 GNB1 UPF3B UPF3B FAM49B FAM49B FMR1 FMR1 ELAVL1 ELAVL1 RPL22 RPL22 RBM8A RBM8A ZNRF1 ZNRF1 PMEPA1 PMEPA1 SERF2 SERF2 NRXN1 NRXN1 GAD1 GAD1 BDNF BDNF TEX2 TEX2 DLX5 DLX5 SH3GLB1 SH3GLB1 PPP2R1B PPP2R1B GAPDH GAPDH NLGN1 NLGN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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FGF2Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family. (155 aa)
RBFOX1RNA binding protein fox-1 homolog 1; RNA-binding protein that regulates alternative splicing events. (369 aa)
LRRC40Leucine rich repeat containing 40. (602 aa)
RAB23RAB23, member RAS oncogene family. (248 aa)
GNB1G protein subunit beta 1. (340 aa)
UPF3BUPF3B regulator of nonsense mediated mRNA decay. (483 aa)
FAM49BFamily with sequence similarity 49 member B. (324 aa)
FMR1Fragile X mental retardation 1. (632 aa)
ELAVL1ELAV-like protein; Belongs to the RRM elav family. (382 aa)
RPL22Uncharacterized protein. (128 aa)
RBM8ARNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (174 aa)
ZNRF1Zinc and ring finger 1. (228 aa)
PMEPA1Prostate transmembrane protein, androgen induced 1. (291 aa)
SERF2Small EDRK-rich factor 2. (169 aa)
NRXN1Neurexin 1. (1507 aa)
GAD1Glutamate decarboxylase 1. (707 aa)
BDNFBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (265 aa)
TEX2Testis expressed 2. (1134 aa)
DLX5Distal-less homeobox 5. (313 aa)
SH3GLB1SH3 domain containing GRB2 like, endophilin B1. (588 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (714 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (333 aa)
NLGN1Neuroligin 1. (823 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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