STRINGSTRING
LIF LIF CNTF CNTF CTF1 CTF1 JAK1 JAK1 CSF3 CSF3 OSM OSM STAT3 STAT3 VCAM1 VCAM1 OSMR OSMR IL21 IL21 JAK2 JAK2 IL6 IL6 HPRT1 HPRT1 G1TVI4_RABIT G1TVI4_RABIT CD34 CD34 TAC1 TAC1 STAT1 STAT1 LIFR LIFR CSF2 CSF2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LIFLIF interleukin 6 family cytokine. (203 aa)
CNTFCiliary neurotrophic factor; CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy. (199 aa)
CTF1Cardiotrophin 1. (190 aa)
JAK1Tyrosine-protein kinase. (1151 aa)
CSF3Colony stimulating factor 3. (204 aa)
OSMUncharacterized protein. (333 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
VCAM1Uncharacterized protein. (828 aa)
OSMROncostatin M receptor. (1088 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (154 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (241 aa)
HPRT1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa)
G1TVI4_RABITNR LBD domain-containing protein. (321 aa)
CD34CD34 molecule. (415 aa)
TAC1C-terminal-flanking peptide; Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles; Belongs to the tachykinin family. (241 aa)
STAT1Signal transducer and activator of transcription. (879 aa)
LIFRLIF receptor subunit alpha. (1091 aa)
CSF2Uncharacterized protein. (144 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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