(9 nodes) (2020) Zhenqing recipe attenuates non-alcoholic fatty liver disease by regulating the SIK1CRTC2 signaling in experimental diabetic rats. network (Oryctolagus cuniculus)

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Your Input:
	PXDNL	Peroxidasin like. (1467 aa)
	FOXO1	Fork-head domain-containing protein. (613 aa)
	CRTC2	CREB regulated transcription coactivator 2. (652 aa)
	G6PC	Glucose-6-phosphatase catalytic subunit. (359 aa)
	INS	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (164 aa)
	PXDN	Peroxidasin. (1411 aa)
	G6PC3	Glucose-6-phosphatase catalytic subunit 3. (562 aa)
	PRKACB	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
	G6PC2	Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (355 aa)

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRTC2	FOXO1	ENSOCUP00000013514	ENSOCUP00000012389	CREB regulated transcription coactivator 2.	Fork-head domain-containing protein.	0.659
CRTC2	G6PC	ENSOCUP00000013514	ENSOCUP00000013761	CREB regulated transcription coactivator 2.	Glucose-6-phosphatase catalytic subunit.	0.612
CRTC2	G6PC2	ENSOCUP00000013514	ENSOCUP00000001179	CREB regulated transcription coactivator 2.	Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family.	0.532
CRTC2	G6PC3	ENSOCUP00000013514	ENSOCUP00000033043	CREB regulated transcription coactivator 2.	Glucose-6-phosphatase catalytic subunit 3.	0.542
CRTC2	INS	ENSOCUP00000013514	ENSOCUP00000020463	CREB regulated transcription coactivator 2.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.520
CRTC2	PRKACB	ENSOCUP00000013514	ENSOCUP00000043583	CREB regulated transcription coactivator 2.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.461
FOXO1	CRTC2	ENSOCUP00000012389	ENSOCUP00000013514	Fork-head domain-containing protein.	CREB regulated transcription coactivator 2.	0.659
FOXO1	G6PC	ENSOCUP00000012389	ENSOCUP00000013761	Fork-head domain-containing protein.	Glucose-6-phosphatase catalytic subunit.	0.856
FOXO1	G6PC2	ENSOCUP00000012389	ENSOCUP00000001179	Fork-head domain-containing protein.	Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family.	0.790
FOXO1	G6PC3	ENSOCUP00000012389	ENSOCUP00000033043	Fork-head domain-containing protein.	Glucose-6-phosphatase catalytic subunit 3.	0.785
FOXO1	INS	ENSOCUP00000012389	ENSOCUP00000020463	Fork-head domain-containing protein.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.878
FOXO1	PRKACB	ENSOCUP00000012389	ENSOCUP00000043583	Fork-head domain-containing protein.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.954
FOXO1	PXDN	ENSOCUP00000012389	ENSOCUP00000022906	Fork-head domain-containing protein.	Peroxidasin.	0.727
FOXO1	PXDNL	ENSOCUP00000012389	ENSOCUP00000004823	Fork-head domain-containing protein.	Peroxidasin like.	0.727
G6PC	CRTC2	ENSOCUP00000013761	ENSOCUP00000013514	Glucose-6-phosphatase catalytic subunit.	CREB regulated transcription coactivator 2.	0.612
G6PC	FOXO1	ENSOCUP00000013761	ENSOCUP00000012389	Glucose-6-phosphatase catalytic subunit.	Fork-head domain-containing protein.	0.856
G6PC	G6PC2	ENSOCUP00000013761	ENSOCUP00000001179	Glucose-6-phosphatase catalytic subunit.	Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family.	0.939
G6PC	G6PC3	ENSOCUP00000013761	ENSOCUP00000033043	Glucose-6-phosphatase catalytic subunit.	Glucose-6-phosphatase catalytic subunit 3.	0.910
G6PC	INS	ENSOCUP00000013761	ENSOCUP00000020463	Glucose-6-phosphatase catalytic subunit.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.817
G6PC2	CRTC2	ENSOCUP00000001179	ENSOCUP00000013514	Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family.	CREB regulated transcription coactivator 2.	0.532