STRINGSTRING
LOC103345451 LOC103345451 TMEM119 TMEM119 TGFBR2 TGFBR2 G1TC56_RABIT G1TC56_RABIT FOXP3 FOXP3 TGFB2 TGFB2 CSF1R CSF1R TGFBR1 TGFBR1 ENSOCUP00000037329 ENSOCUP00000037329 ENSOCUP00000044284 ENSOCUP00000044284 S100B S100B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103345451TGFb_propeptide domain-containing protein. (203 aa)
TMEM119Transmembrane protein 119. (337 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
G1TC56_RABITTGFb_propeptide domain-containing protein. (168 aa)
FOXP3Forkhead box P3. (455 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (973 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (486 aa)
ENSOCUP00000037329TGFb_propeptide domain-containing protein. (263 aa)
ENSOCUP00000044284TGFb_propeptide domain-containing protein. (260 aa)
S100BProtein S100-B; Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic pr [...] (92 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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