STRINGSTRING
VIM VIM G1SV95_RABIT G1SV95_RABIT NCK1 NCK1 TGFB2 TGFB2 CHD1 CHD1 NEDD8 NEDD8 CUL1 CUL1 CUL7 CUL7 ITGA6 ITGA6 ALB ALB UBE2M UBE2M GATA3 GATA3 NCK2 NCK2 CUL3 CUL3 ITGA1 ITGA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
VIMVimentin; Belongs to the intermediate filament family. (466 aa)
G1SV95_RABITTransforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
NCK1Cytoplasmic protein. (377 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
CHD1Chromodomain helicase DNA binding protein 1. (1537 aa)
NEDD8NEDD8; Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins (By similarity). (81 aa)
CUL1Cullin 1; Belongs to the cullin family. (775 aa)
CUL7Cullin 7; Belongs to the cullin family. (1728 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (955 aa)
ALBSerum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] (608 aa)
UBE2MUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (457 aa)
GATA3GATA binding protein 3. (444 aa)
NCK2Cytoplasmic protein. (380 aa)
CUL3Cullin 3; Belongs to the cullin family. (771 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1178 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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