STRINGSTRING
ZNF692 ZNF692 CUL7 CUL7 DDB1 DDB1 DDB2 DDB2 CUL1 CUL1 ZFP91 ZFP91 ETF1 ETF1 IRF4 IRF4 CUL4A CUL4A CUL5 CUL5 ATOH1 ATOH1 CUL2 CUL2 CDT1 CDT1 UBE2G1 UBE2G1 SALL4 SALL4 CUL4B CUL4B SIRT2 SIRT2 UBE2D3 UBE2D3 MEIS2 MEIS2 SP1 SP1 CUL3 CUL3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ZNF692Zinc finger protein 692. (657 aa)
CUL7Cullin 7; Belongs to the cullin family. (1728 aa)
DDB1Damage specific DNA binding protein 1. (1140 aa)
DDB2Damage specific DNA binding protein 2. (427 aa)
CUL1Cullin 1; Belongs to the cullin family. (775 aa)
ZFP91Uncharacterized protein. (482 aa)
ETF1Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular genes. (437 aa)
IRF4Interferon regulatory factor 4. (451 aa)
CUL4ACullin 4A; Belongs to the cullin family. (759 aa)
CUL5Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...] (780 aa)
ATOH1Atonal bHLH transcription factor 1. (359 aa)
CUL2Cullin 2; Belongs to the cullin family. (745 aa)
CDT1Chromatin licensing and DNA replication factor 1. (365 aa)
UBE2G1UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (170 aa)
SALL4Spalt like transcription factor 4. (994 aa)
CUL4BCullin 4B; Belongs to the cullin family. (901 aa)
SIRT2Sirtuin 2. (509 aa)
UBE2D3Ubiquitin conjugating enzyme E2 D3; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
MEIS2Meis homeobox 2. (477 aa)
SP1Sp1 transcription factor. (792 aa)
CUL3Cullin 3; Belongs to the cullin family. (771 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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