STRINGSTRING
METTL3 METTL3 IKZF3 IKZF3 LYN LYN METTL14 METTL14 ALPL ALPL EBF1 EBF1 IRF4 IRF4 G1SXE4_RABIT G1SXE4_RABIT PTPRC PTPRC MCL1 MCL1 CDKN1B CDKN1B FOXO1 FOXO1 CD93 CD93 SYK SYK IGLL1 IGLL1 YTHDF2 YTHDF2 MX1 MX1 SPIB SPIB HPRT1 HPRT1 IGHM-2 IGHM-2 METTL16 METTL16 RAG1 RAG1 RAG2 RAG2 IGHM-3 IGHM-3 YTHDF1 YTHDF1 LOC100347353 LOC100347353 CD79B CD79B KIT KIT BCL2 BCL2 CD19 CD19 IL7 IL7 CCND3 CCND3 BCL6 BCL6 ENSOCUP00000047465 ENSOCUP00000047465 WTAP WTAP DNTT DNTT
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
METTL3Methyltransferase like 3; Belongs to the MT-A70-like family. (580 aa)
IKZF3IKAROS family zinc finger 3. (509 aa)
LYNTyrosine-protein kinase. (636 aa)
METTL14Methyltransferase like 14; Belongs to the MT-A70-like family. (434 aa)
ALPLAlkaline phosphatase. (558 aa)
EBF1EBF transcription factor 1. (591 aa)
IRF4Interferon regulatory factor 4. (451 aa)
G1SXE4_RABITAlkaline phosphatase. (533 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1310 aa)
MCL1MCL1 apoptosis regulator, BCL2 family member. (352 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
FOXO1Fork-head domain-containing protein. (613 aa)
CD93CD93 molecule. (653 aa)
SYKTyrosine-protein kinase. (630 aa)
IGLL1Lambda5. (208 aa)
YTHDF2YTH N6-methyladenosine RNA binding protein 2. (579 aa)
MX1Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (697 aa)
SPIBETS domain-containing protein. (158 aa)
HPRT1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa)
IGHM-2Ig-like domain-containing protein. (167 aa)
METTL16U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] (562 aa)
RAG1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1128 aa)
RAG2V(D)J recombination-activating protein 2; Core component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T- cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. DNA cleavage by the RAG complex occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the pho [...] (527 aa)
IGHM-3Ig-like domain-containing protein. (167 aa)
YTHDF1YTH N6-methyladenosine RNA binding protein 1. (652 aa)
LOC100347353Alkaline phosphatase. (556 aa)
CD79BCD79b molecule. (282 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (970 aa)
BCL2BH4_2 domain-containing protein. (389 aa)
CD19CD19 molecule. (573 aa)
IL7Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (175 aa)
CCND3Cyclin D3; Belongs to the cyclin family. (287 aa)
BCL6BCL6 transcription repressor. (723 aa)
ENSOCUP00000047465Alkaline phosphatase. (573 aa)
WTAPWT1 associated protein. (448 aa)
DNTTDNA nucleotidylexotransferase; Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. (569 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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