STRINGSTRING
SUMO2 SUMO2 CUL1 CUL1 NEDD8 NEDD8 G1SQP5_RABIT G1SQP5_RABIT SAMHD1 SAMHD1 CUL4A CUL4A CUL2 CUL2 G1TG12_RABIT G1TG12_RABIT G1TM59_RABIT G1TM59_RABIT G1TU65_RABIT G1TU65_RABIT CUL3 CUL3 SUMO1 SUMO1 ENSOCUP00000041916 ENSOCUP00000041916
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SUMO2Small ubiquitin-related modifier. (95 aa)
CUL1Cullin 1; Belongs to the cullin family. (775 aa)
NEDD8NEDD8; Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins (By similarity). (81 aa)
G1SQP5_RABITSmall ubiquitin-related modifier. (95 aa)
SAMHD1SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1. (616 aa)
CUL4ACullin 4A; Belongs to the cullin family. (759 aa)
CUL2Cullin 2; Belongs to the cullin family. (745 aa)
G1TG12_RABITSmall ubiquitin-related modifier. (87 aa)
G1TM59_RABITSmall ubiquitin-related modifier. (94 aa)
G1TU65_RABITSmall ubiquitin-related modifier. (95 aa)
CUL3Cullin 3; Belongs to the cullin family. (771 aa)
SUMO1Small ubiquitin-related modifier. (101 aa)
ENSOCUP00000041916Small ubiquitin-related modifier. (109 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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