STRINGSTRING
DNTT DNTT MEIS1 MEIS1 CD9 CD9 MPO MPO PF4 PF4 CCNE1 CCNE1 MYL4 MYL4 KLF1 KLF1 CD19 CD19 KIT KIT CENPT CENPT CD79B CD79B CD34 CD34 GATA1 GATA1 GFI1 GFI1 VPREB1-2 VPREB1-2 VPREB3 VPREB3 CEBPA CEBPA FOS FOS RAG1 RAG1 HOXA9 HOXA9 CD3E CD3E LDB1 LDB1 VPREB1 VPREB1 CEBPB CEBPB HOXB8 HOXB8 IGLL1 IGLL1 ANXA3 ANXA3 GATA3 GATA3 TAL1 TAL1 PROCR PROCR IKZF1 IKZF1 RUNX1 RUNX1 PAX5 PAX5 RUNX2 RUNX2 MYB MYB IL7R IL7R MS4A2 MS4A2 EBF1 EBF1 MZB1 MZB1 AFAP1 AFAP1 PREB PREB FLT3 FLT3 CCNB1 CCNB1 RAD21 RAD21 GFI1B GFI1B LMO2 LMO2 CTSG CTSG MMP8 MMP8 IRF8 IRF8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DNTTDNA nucleotidylexotransferase; Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. (569 aa)
MEIS1Meis homeobox 1. (465 aa)
CD9Tetraspanin. (385 aa)
MPOMyeloperoxidase. (725 aa)
PF4Platelet factor 4; Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation (By similarity); Belongs to the intercrine alpha (chemokine CxC) family. (105 aa)
CCNE1Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (436 aa)
MYL4Myosin light chain 4. (230 aa)
KLF1C2H2-type domain-containing protein. (553 aa)
CD19CD19 molecule. (573 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (970 aa)
CENPTCENP-T_N domain-containing protein. (75 aa)
CD79BCD79b molecule. (282 aa)
CD34CD34 molecule. (415 aa)
GATA1GATA binding protein 1. (413 aa)
GFI1Growth factor independent 1 transcriptional repressor. (423 aa)
VPREB1-2Ig-like domain-containing protein. (147 aa)
VPREB3V-set pre-B cell surrogate light chain 3. (123 aa)
CEBPACCAAT enhancer binding protein alpha. (402 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
RAG1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1128 aa)
HOXA9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (276 aa)
CD3ET-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...] (201 aa)
LDB1LIM domain binding 1. (410 aa)
VPREB1Ig-like domain-containing protein. (147 aa)
CEBPBCCAAT enhancer binding protein beta. (353 aa)
HOXB8Homeobox B8. (151 aa)
IGLL1Lambda5. (208 aa)
ANXA3Annexin. (323 aa)
GATA3GATA binding protein 3. (444 aa)
TAL1TAL bHLH transcription factor 1, erythroid differentiation factor. (319 aa)
PROCRProtein C receptor. (240 aa)
IKZF1IKAROS family zinc finger 1. (515 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (466 aa)
PAX5Paired box 5. (371 aa)
RUNX2RUNX family transcription factor 2. (343 aa)
MYBMYB proto-oncogene, transcription factor. (758 aa)
IL7RInterleukin 7 receptor. (458 aa)
MS4A2Membrane spanning 4-domains A2. (243 aa)
EBF1EBF transcription factor 1. (591 aa)
MZB1Marginal zone B and B1 cell specific protein. (187 aa)
AFAP1Actin filament associated protein 1. (642 aa)
PREBProlactin regulatory element binding. (418 aa)
FLT3Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (993 aa)
CCNB1Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (844 aa)
RAD21RAD21 cohesin complex component. (630 aa)
GFI1BGrowth factor independent 1B transcriptional repressor. (395 aa)
LMO2LIM domain only 2. (158 aa)
CTSGCathepsin G. (250 aa)
MMP8Matrix metallopeptidase 8. (355 aa)
IRF8Interferon regulatory factor 8. (455 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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