35 items (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RPS23	Uncharacterized protein. (242 aa)
	RPL21	Uncharacterized protein. (160 aa)
	GUSB	Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. (645 aa)
	SF3B3	Splicing factor 3b subunit 3. (1189 aa)
	SF3B4	Splicing factor 3b subunit 4. (424 aa)
	DDX17	DEAD-box helicase 17; Belongs to the DEAD box helicase family. (716 aa)
	USP18	USP domain-containing protein; Belongs to the peptidase C19 family. (373 aa)
	RPL27A	Ribosomal_L18e/L15P domain-containing protein; Belongs to the universal ribosomal protein uL15 family. (148 aa)
	DDX60	DExD/H-box helicase 60. (1710 aa)
	IFI44	Interferon induced protein 44. (451 aa)
	DDX1	DEAD-box helicase 1. (740 aa)
	SF3B2	Splicing factor 3b subunit 2. (869 aa)
	CMPK2	Cytidine/uridine monophosphate kinase 2. (451 aa)
	RSAD2	Radical S-adenosyl methionine domain containing 2. (396 aa)
	MYC	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (438 aa)
	OAS2	2'-5'-oligoadenylate synthetase 2. (685 aa)
	MX1	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (697 aa)
	OAS3	2'-5'-oligoadenylate synthetase 3. (1119 aa)
	LOC100348511	S10_plectin domain-containing protein. (165 aa)
	DDX58	DExD/H-box helicase 58. (954 aa)
	FUS	FUS RNA binding protein. (517 aa)
	IFIT2	Interferon induced protein with tetratricopeptide repeats 2. (472 aa)
	G1TXX4_RABIT	Uncharacterized protein. (149 aa)
	RPS23-2	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family. (143 aa)
	RPS15	Ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family. (145 aa)
	ENSOCUP00000023841	annotation not available (160 aa)
	EWSR1	Uncharacterized protein. (660 aa)
	ISG15	ISG15 ubiquitin like modifier. (164 aa)
	IFIT3	Interferon induced protein with tetratricopeptide repeats 3. (484 aa)
	RPS18	Uncharacterized protein. (166 aa)
	STAT1	Signal transducer and activator of transcription. (879 aa)
	AR	Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. (925 aa)
	RPS18-2	Uncharacterized protein. (310 aa)
	RPS10	S10_plectin domain-containing protein. (229 aa)
	OAS1	2'-5'-oligoadenylate synthetase 1. (358 aa)

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AR	MYC	ENSOCUP00000042647	ENSOCUP00000012281	Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.	0.712
AR	STAT1	ENSOCUP00000042647	ENSOCUP00000039721	Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.	Signal transducer and activator of transcription.	0.617
CMPK2	DDX58	ENSOCUP00000008630	ENSOCUP00000019472	Cytidine/uridine monophosphate kinase 2.	DExD/H-box helicase 58.	0.614
CMPK2	DDX60	ENSOCUP00000008630	ENSOCUP00000005504	Cytidine/uridine monophosphate kinase 2.	DExD/H-box helicase 60.	0.693
CMPK2	IFI44	ENSOCUP00000008630	ENSOCUP00000005604	Cytidine/uridine monophosphate kinase 2.	Interferon induced protein 44.	0.702
CMPK2	IFIT2	ENSOCUP00000008630	ENSOCUP00000021806	Cytidine/uridine monophosphate kinase 2.	Interferon induced protein with tetratricopeptide repeats 2.	0.716
CMPK2	IFIT3	ENSOCUP00000008630	ENSOCUP00000030015	Cytidine/uridine monophosphate kinase 2.	Interferon induced protein with tetratricopeptide repeats 3.	0.729
CMPK2	ISG15	ENSOCUP00000008630	ENSOCUP00000029108	Cytidine/uridine monophosphate kinase 2.	ISG15 ubiquitin like modifier.	0.682
CMPK2	MX1	ENSOCUP00000008630	ENSOCUP00000016943	Cytidine/uridine monophosphate kinase 2.	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.804
CMPK2	OAS1	ENSOCUP00000008630	ENSOCUP00000045448	Cytidine/uridine monophosphate kinase 2.	2'-5'-oligoadenylate synthetase 1.	0.550
CMPK2	OAS2	ENSOCUP00000008630	ENSOCUP00000013595	Cytidine/uridine monophosphate kinase 2.	2'-5'-oligoadenylate synthetase 2.	0.557
CMPK2	OAS3	ENSOCUP00000008630	ENSOCUP00000017766	Cytidine/uridine monophosphate kinase 2.	2'-5'-oligoadenylate synthetase 3.	0.572
CMPK2	RSAD2	ENSOCUP00000008630	ENSOCUP00000010461	Cytidine/uridine monophosphate kinase 2.	Radical S-adenosyl methionine domain containing 2.	0.961
CMPK2	STAT1	ENSOCUP00000008630	ENSOCUP00000039721	Cytidine/uridine monophosphate kinase 2.	Signal transducer and activator of transcription.	0.524
CMPK2	USP18	ENSOCUP00000008630	ENSOCUP00000004393	Cytidine/uridine monophosphate kinase 2.	USP domain-containing protein; Belongs to the peptidase C19 family.	0.897
DDX1	DDX17	ENSOCUP00000006066	ENSOCUP00000004311	DEAD-box helicase 1.	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	0.452
DDX1	DDX60	ENSOCUP00000006066	ENSOCUP00000005504	DEAD-box helicase 1.	DExD/H-box helicase 60.	0.729
DDX1	FUS	ENSOCUP00000006066	ENSOCUP00000020899	DEAD-box helicase 1.	FUS RNA binding protein.	0.526
DDX1	MYC	ENSOCUP00000006066	ENSOCUP00000012281	DEAD-box helicase 1.	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.	0.449
DDX1	RPL27A	ENSOCUP00000006066	ENSOCUP00000004720	DEAD-box helicase 1.	Ribosomal_L18e/L15P domain-containing protein; Belongs to the universal ribosomal protein uL15 family.	0.425