node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALB | GOT2 | ENSOCUP00000014006 | ENSOCUP00000047949 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Aspartate aminotransferase, mitochondrial; Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity). | 0.586 |
ALB | IL6 | ENSOCUP00000014006 | ENSOCUP00000017266 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] | 0.899 |
ALB | LOC103350073 | ENSOCUP00000014006 | ENSOCUP00000006271 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. | 0.589 |
ALB | MT1B | ENSOCUP00000014006 | ENSOCUP00000047546 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. | 0.580 |
ALB | MT4 | ENSOCUP00000014006 | ENSOCUP00000014837 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. | 0.588 |
ALB | NPY | ENSOCUP00000014006 | ENSOCUP00000009261 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Neuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. | 0.649 |
ALB | OCLN | ENSOCUP00000014006 | ENSOCUP00000004293 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. | 0.814 |
ATOX1 | ATP7A | ENSOCUP00000046347 | ENSOCUP00000012171 | Antioxidant 1 copper chaperone. | ATPase copper transporting alpha. | 0.995 |
ATOX1 | ATP7B | ENSOCUP00000046347 | ENSOCUP00000043559 | Antioxidant 1 copper chaperone. | ATPase copper transporting beta. | 0.992 |
ATOX1 | COX17 | ENSOCUP00000046347 | ENSOCUP00000022619 | Antioxidant 1 copper chaperone. | Cytochrome c oxidase copper chaperone COX17. | 0.930 |
ATOX1 | LOC103350073 | ENSOCUP00000046347 | ENSOCUP00000006271 | Antioxidant 1 copper chaperone. | Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. | 0.654 |
ATOX1 | MT1B | ENSOCUP00000046347 | ENSOCUP00000047546 | Antioxidant 1 copper chaperone. | Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. | 0.654 |
ATOX1 | MT4 | ENSOCUP00000046347 | ENSOCUP00000014837 | Antioxidant 1 copper chaperone. | Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. | 0.794 |
ATP7A | ATOX1 | ENSOCUP00000012171 | ENSOCUP00000046347 | ATPase copper transporting alpha. | Antioxidant 1 copper chaperone. | 0.995 |
ATP7A | ATP7B | ENSOCUP00000012171 | ENSOCUP00000043559 | ATPase copper transporting alpha. | ATPase copper transporting beta. | 0.905 |
ATP7A | COX17 | ENSOCUP00000012171 | ENSOCUP00000022619 | ATPase copper transporting alpha. | Cytochrome c oxidase copper chaperone COX17. | 0.874 |
ATP7A | LOC103350073 | ENSOCUP00000012171 | ENSOCUP00000006271 | ATPase copper transporting alpha. | Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. | 0.728 |
ATP7A | MT1B | ENSOCUP00000012171 | ENSOCUP00000047546 | ATPase copper transporting alpha. | Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. | 0.727 |
ATP7A | MT4 | ENSOCUP00000012171 | ENSOCUP00000014837 | ATPase copper transporting alpha. | Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. | 0.728 |
ATP7B | ATOX1 | ENSOCUP00000043559 | ENSOCUP00000046347 | ATPase copper transporting beta. | Antioxidant 1 copper chaperone. | 0.992 |