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| | CS | Citrate synthase; Belongs to the citrate synthase family. (466 aa) |
| | KDM5A | Transporter. (2271 aa) |
| | HADHB | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (475 aa) |
| | GYS1 | Glycogen [starch] synthase, muscle; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (735 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (391 aa) |
| | COX4I1 | Cytochrome c oxidase subunit 4 isoform 1, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives tran [...] (169 aa) |
| | TNNT3 | Troponin T, fast skeletal muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. (202 aa) |
| | PYGM | Glycogen phosphorylase, muscle form; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (829 aa) |
| | OGDH | Oxoglutarate dehydrogenase. (1050 aa) |
| | PDHA2 | Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (391 aa) |
| | PYGB | Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (831 aa) |
| | MYH4 | Myosin-4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1939 aa) |
| | ENO2 | Beta-enolase; Appears to have a function in striated muscle development and regeneration; Belongs to the enolase family. (434 aa) |
| | ATP5F1A | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (553 aa) |
| | ACTA1 | Actin, alpha skeletal muscle. (369 aa) |
| | ATP5F1C | ATP synthase subunit gamma. (298 aa) |
| | PXDNL | Peroxidasin like. (1467 aa) |
| | LUM | Lumican. (338 aa) |
| | ATP5F1B | ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (528 aa) |
| | NDUFS3 | NADH:ubiquinone oxidoreductase core subunit S3; Belongs to the complex I 30 kDa subunit family. (263 aa) |
| | LOC100349893 | Uncharacterized protein; Belongs to the tropomyosin family. (205 aa) |
| | COL6A3 | Uncharacterized protein. (562 aa) |
| | ACTC1 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. (377 aa) |
| | VIM | Vimentin; Belongs to the intermediate filament family. (466 aa) |
| | VDAC1 | Voltage-dependent anion-selective channel protein 1; Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. May participate in the formation of the permeability transition p [...] (283 aa) |
| | CFL2 | Cofilin 2; Belongs to the actin-binding proteins ADF family. (195 aa) |
| | HADHA | Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (797 aa) |
| | MYH8 | Myosin heavy chain 8; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1937 aa) |
| | COL1A2 | Collagen alpha-2(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family. (1364 aa) |
| | NDUFS1 | NADH:ubiquinone oxidoreductase core subunit S1; Belongs to the complex I 75 kDa subunit family. (727 aa) |
| | COL1A1 | Collagen alpha-1(I) chain. (1348 aa) |
| | MYOM2 | Myomesin 2. (1415 aa) |
| | UQCRQ | Uncharacterized protein. (82 aa) |
| | TPM1 | Tropomyosin alpha-1 chain; Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments; Belongs to the tropomyosin family. (326 aa) |
| | MYOT | Myotilin. (806 aa) |
| | PGK1 | Phosphoglycerate kinase. (417 aa) |
| | PKLR | Pyruvate kinase; Belongs to the pyruvate kinase family. (574 aa) |
| | PYGL | Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (851 aa) |
| | PDHB | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (359 aa) |
| | LDHA | L-lactate dehydrogenase A chain. (430 aa) |
| | MYLPF | Myosin regulatory light chain 2, skeletal muscle isoform type 2. (200 aa) |
| | G1TJG6_RABIT | Glyceraldehyde-3-phosphate dehydrogenase. (305 aa) |
| | MYBPC1 | Myosin binding protein C, slow type. (1173 aa) |
| | MYH1 | Myosin-4; Muscle contraction. (1938 aa) |
| | NDUFA9 | NADH:ubiquinone oxidoreductase subunit A9. (377 aa) |
| | MYOZ1 | Uncharacterized protein. (310 aa) |
| | TPI1 | Triosephosphate isomerase; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis. (288 aa) |
| | AGL | Amylo-alpha-1,6-glucosidase; Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4- alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation. (1532 aa) |
| | INS | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (164 aa) |
| | ACO2 | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (798 aa) |
| | MYH7 | Myosin-7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1935 aa) |
| | G1TYG1_RABIT | Glyceraldehyde-3-phosphate dehydrogenase. (369 aa) |
| | TMOD4 | Tropomodulin 4 (Predicted). (345 aa) |
| | COX5A | Cytochrome c oxidase subunit 5A. (182 aa) |
| | PXDN | Peroxidasin. (1411 aa) |
| | ENO3 | Beta-enolase. (352 aa) |
| | PGAM2 | Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (253 aa) |
| | CLPP | ATP-dependent Clp protease proteolytic subunit. (189 aa) |
| | COX1 | Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (513 aa) |
| | ACADM | Acyl-CoA dehydrogenase medium chain. (474 aa) |
| | MYL2 | Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; Contractile protein that plays a role in heart development and function (By similarity). Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin [...] (232 aa) |
| | MYL3 | Myosin light chain 3. (327 aa) |
| | PDLIM5 | PDZ and LIM domain 5. (687 aa) |
| | PPARGC1A | PPARG coactivator 1 alpha. (860 aa) |
| | MDH2 | Malate dehydrogenase 2. (518 aa) |
| | ENO1 | Uncharacterized protein. (511 aa) |
| | GPI | Glucose-6-phosphate isomerase; In the cytoplasm, catalyzes the conversion of glucose-6- phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis (By similarity). Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion (By similarity). (588 aa) |
| | LDHB | L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (334 aa) |
| | MYL1 | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. (193 aa) |
| | TTN | Uncharacterized protein. (569 aa) |
| | FHL1 | Four and a half LIM domains 1. (348 aa) |
| | SUCLG1 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (361 aa) |
| | HIF1A | Uncharacterized protein. (851 aa) |
| | ALDOA | Fructose-bisphosphate aldolase A; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein. Belongs to the class I fructose-bisphosphate aldolase family. (419 aa) |
| | NDUFA10 | dNK domain-containing protein. (444 aa) |
| | ACO1 | Cytoplasmic aconitate hydratase; Iron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Functions as mRNA binding protein that regulates uptake, sequestration and utilization of iron when cellular iron levels are low. Binds to iron-responsive elements (IRES) in target mRNA species when iron levels are low. Binding of a 4Fe-4S cluster precludes RNA binding; Belongs to the aconitase/IPM isomerase family. (1080 aa) |
| | PPARG | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa) |
| | GAPDH | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (333 aa) |
| | IDH3A | Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (464 aa) |
| | ENSOCUP00000045683 | Pyruvate kinase; Belongs to the pyruvate kinase family. (144 aa) |
| | CPT1B | Carnitine palmitoyltransferase 1B; Belongs to the carnitine/choline acetyltransferase family. (495 aa) |
| | UQCRC1 | Ubiquinol-cytochrome c reductase core protein 1. (539 aa) |
| | ACTB | Uncharacterized protein. (357 aa) |
| | FLNC | Filamin C. (2628 aa) |
| | VDAC2 | Voltage-dependent anion-selective channel protein 2; Forms a channel through the cell membrane that allows diffusion from small hydrophilic molecules. (439 aa) |
| | NEB | Nebulin. (6666 aa) |
| | IDH2 | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (470 aa) |
| | PDHA1 | Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (399 aa) |
