| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALB | CA1 | ENSOCUP00000014006 | ENSOCUP00000004364 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Carbonic anhydrase 1; Reversible hydration of carbon dioxide. | 0.459 |
| ALB | CA4 | ENSOCUP00000014006 | ENSOCUP00000046147 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Carbonic anhydrase 4; Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 (By similarity). | 0.471 |
| ALB | CA9 | ENSOCUP00000014006 | ENSOCUP00000008783 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Carbonic anhydrase 9; Belongs to the alpha-carbonic anhydrase family. | 0.497 |
| ALB | GFAP | ENSOCUP00000014006 | ENSOCUP00000034730 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Glial fibrillary acidic protein; Belongs to the intermediate filament family. | 0.866 |
| ALB | IL10 | ENSOCUP00000014006 | ENSOCUP00000019534 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] | 0.859 |
| ALB | PLAT | ENSOCUP00000014006 | ENSOCUP00000042684 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Uncharacterized protein. | 0.656 |
| CA1 | ALB | ENSOCUP00000004364 | ENSOCUP00000014006 | Carbonic anhydrase 1; Reversible hydration of carbon dioxide. | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | 0.459 |
| CA12 | CA14 | ENSOCUP00000031976 | ENSOCUP00000007798 | Carbonic anhydrase 12; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. | Carbonic anhydrase 14; Belongs to the alpha-carbonic anhydrase family. | 0.490 |
| CA12 | CA4 | ENSOCUP00000031976 | ENSOCUP00000046147 | Carbonic anhydrase 12; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. | Carbonic anhydrase 4; Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 (By similarity). | 0.606 |
| CA12 | CA9 | ENSOCUP00000031976 | ENSOCUP00000008783 | Carbonic anhydrase 12; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. | Carbonic anhydrase 9; Belongs to the alpha-carbonic anhydrase family. | 0.552 |
| CA13 | CA4 | ENSOCUP00000036484 | ENSOCUP00000046147 | Carbonic anhydrase 13; Belongs to the alpha-carbonic anhydrase family. | Carbonic anhydrase 4; Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 (By similarity). | 0.421 |
| CA13 | CA7 | ENSOCUP00000036484 | ENSOCUP00000032002 | Carbonic anhydrase 13; Belongs to the alpha-carbonic anhydrase family. | Carbonic anhydrase 7; Belongs to the alpha-carbonic anhydrase family. | 0.437 |
| CA14 | CA12 | ENSOCUP00000007798 | ENSOCUP00000031976 | Carbonic anhydrase 14; Belongs to the alpha-carbonic anhydrase family. | Carbonic anhydrase 12; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. | 0.490 |
| CA14 | CA4 | ENSOCUP00000007798 | ENSOCUP00000046147 | Carbonic anhydrase 14; Belongs to the alpha-carbonic anhydrase family. | Carbonic anhydrase 4; Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 (By similarity). | 0.560 |
| CA14 | CA9 | ENSOCUP00000007798 | ENSOCUP00000008783 | Carbonic anhydrase 14; Belongs to the alpha-carbonic anhydrase family. | Carbonic anhydrase 9; Belongs to the alpha-carbonic anhydrase family. | 0.461 |
| CA3 | CA7 | ENSOCUP00000026583 | ENSOCUP00000032002 | Carbonic anhydrase 3; Belongs to the alpha-carbonic anhydrase family. | Carbonic anhydrase 7; Belongs to the alpha-carbonic anhydrase family. | 0.492 |
| CA4 | ALB | ENSOCUP00000046147 | ENSOCUP00000014006 | Carbonic anhydrase 4; Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 (By similarity). | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | 0.471 |
| CA4 | CA12 | ENSOCUP00000046147 | ENSOCUP00000031976 | Carbonic anhydrase 4; Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 (By similarity). | Carbonic anhydrase 12; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. | 0.606 |
| CA4 | CA13 | ENSOCUP00000046147 | ENSOCUP00000036484 | Carbonic anhydrase 4; Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 (By similarity). | Carbonic anhydrase 13; Belongs to the alpha-carbonic anhydrase family. | 0.421 |
| CA4 | CA14 | ENSOCUP00000046147 | ENSOCUP00000007798 | Carbonic anhydrase 4; Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 (By similarity). | Carbonic anhydrase 14; Belongs to the alpha-carbonic anhydrase family. | 0.560 |