node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATP5F1A | MDH2 | ENSOCUP00000003441 | ENSOCUP00000035179 | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. | Malate dehydrogenase 2. | 0.923 |
ATP5F1A | RPL26 | ENSOCUP00000003441 | ENSOCUP00000005347 | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. | Ribosomal protein L26. | 0.590 |
ATP5F1A | RPL4 | ENSOCUP00000003441 | ENSOCUP00000028125 | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. | Ribos_L4_asso_C domain-containing protein. | 0.652 |
ATP5F1A | SDHB | ENSOCUP00000003441 | ENSOCUP00000031100 | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. | Succinate dehydrogenase complex iron sulfur subunit B. | 0.972 |
FLNA | FLNB | ENSOCUP00000000761 | ENSOCUP00000033274 | Uncharacterized protein. | Filamin-B; Connects cell membrane constituents to the actin cytoskeleton. May promote orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton (By similarity). | 0.536 |
FLNB | FLNA | ENSOCUP00000033274 | ENSOCUP00000000761 | Filamin-B; Connects cell membrane constituents to the actin cytoskeleton. May promote orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton (By similarity). | Uncharacterized protein. | 0.536 |
MARS1 | MARS2 | ENSOCUP00000049774 | ENSOCUP00000024829 | Methionyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | Methionyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.971 |
MARS1 | RPL26 | ENSOCUP00000049774 | ENSOCUP00000005347 | Methionyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | Ribosomal protein L26. | 0.429 |
MARS1 | RPL4 | ENSOCUP00000049774 | ENSOCUP00000028125 | Methionyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | Ribos_L4_asso_C domain-containing protein. | 0.513 |
MARS2 | MARS1 | ENSOCUP00000024829 | ENSOCUP00000049774 | Methionyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. | Methionyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.971 |
MDH2 | ATP5F1A | ENSOCUP00000035179 | ENSOCUP00000003441 | Malate dehydrogenase 2. | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. | 0.923 |
MDH2 | SDHB | ENSOCUP00000035179 | ENSOCUP00000031100 | Malate dehydrogenase 2. | Succinate dehydrogenase complex iron sulfur subunit B. | 0.972 |
MYH1 | MYL2 | ENSOCUP00000017571 | ENSOCUP00000028408 | Myosin-4; Muscle contraction. | Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; Contractile protein that plays a role in heart development and function (By similarity). Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin [...] | 0.856 |
MYH1 | MYLPF | ENSOCUP00000017571 | ENSOCUP00000015491 | Myosin-4; Muscle contraction. | Myosin regulatory light chain 2, skeletal muscle isoform type 2. | 0.876 |
MYH4 | MYL2 | ENSOCUP00000002961 | ENSOCUP00000028408 | Myosin-4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; Contractile protein that plays a role in heart development and function (By similarity). Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin [...] | 0.743 |
MYH4 | MYLPF | ENSOCUP00000002961 | ENSOCUP00000015491 | Myosin-4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | Myosin regulatory light chain 2, skeletal muscle isoform type 2. | 0.761 |
MYL2 | MYH1 | ENSOCUP00000028408 | ENSOCUP00000017571 | Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; Contractile protein that plays a role in heart development and function (By similarity). Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin [...] | Myosin-4; Muscle contraction. | 0.856 |
MYL2 | MYH4 | ENSOCUP00000028408 | ENSOCUP00000002961 | Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; Contractile protein that plays a role in heart development and function (By similarity). Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin [...] | Myosin-4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.743 |
MYL2 | MYLPF | ENSOCUP00000028408 | ENSOCUP00000015491 | Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; Contractile protein that plays a role in heart development and function (By similarity). Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin [...] | Myosin regulatory light chain 2, skeletal muscle isoform type 2. | 0.817 |
MYLPF | MYH1 | ENSOCUP00000015491 | ENSOCUP00000017571 | Myosin regulatory light chain 2, skeletal muscle isoform type 2. | Myosin-4; Muscle contraction. | 0.876 |