node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACTA1 | GAPDH | ENSOCUP00000003527 | ENSOCUP00000044112 | Actin, alpha skeletal muscle. | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] | 0.607 |
ACTA1 | MYF5 | ENSOCUP00000003527 | ENSOCUP00000023250 | Actin, alpha skeletal muscle. | Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. | 0.505 |
ACTA1 | MYH1 | ENSOCUP00000003527 | ENSOCUP00000017571 | Actin, alpha skeletal muscle. | Myosin-4; Muscle contraction. | 0.739 |
ACTA1 | MYH8 | ENSOCUP00000003527 | ENSOCUP00000008830 | Actin, alpha skeletal muscle. | Myosin heavy chain 8; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.713 |
ACTA1 | MYOG | ENSOCUP00000003527 | ENSOCUP00000009928 | Actin, alpha skeletal muscle. | Myogenin. | 0.677 |
ACTA1 | PAX7 | ENSOCUP00000003527 | ENSOCUP00000005326 | Actin, alpha skeletal muscle. | Paired box 7. | 0.433 |
ACTA1 | TNNI1 | ENSOCUP00000003527 | ENSOCUP00000008977 | Actin, alpha skeletal muscle. | Troponin I, slow skeletal muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.666 |
ACTA1 | TNNT3 | ENSOCUP00000003527 | ENSOCUP00000001509 | Actin, alpha skeletal muscle. | Troponin T, fast skeletal muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.803 |
ACTC1 | GAPDH | ENSOCUP00000006542 | ENSOCUP00000044112 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] | 0.685 |
ACTC1 | LMNA | ENSOCUP00000006542 | ENSOCUP00000008626 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Lamin A/C; Belongs to the intermediate filament family. | 0.469 |
ACTC1 | MYF5 | ENSOCUP00000006542 | ENSOCUP00000023250 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. | 0.533 |
ACTC1 | MYH1 | ENSOCUP00000006542 | ENSOCUP00000017571 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Myosin-4; Muscle contraction. | 0.787 |
ACTC1 | MYH8 | ENSOCUP00000006542 | ENSOCUP00000008830 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Myosin heavy chain 8; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.730 |
ACTC1 | MYO1D | ENSOCUP00000006542 | ENSOCUP00000007360 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Myosin ID; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.439 |
ACTC1 | MYOG | ENSOCUP00000006542 | ENSOCUP00000009928 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Myogenin. | 0.658 |
ACTC1 | PAX7 | ENSOCUP00000006542 | ENSOCUP00000005326 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Paired box 7. | 0.438 |
ACTC1 | TNNI1 | ENSOCUP00000006542 | ENSOCUP00000008977 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Troponin I, slow skeletal muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.732 |
ACTC1 | TNNT3 | ENSOCUP00000006542 | ENSOCUP00000001509 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Troponin T, fast skeletal muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.795 |
ANXA3 | GAPDH | ENSOCUP00000015360 | ENSOCUP00000044112 | Annexin. | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] | 0.796 |
ANXA3 | PTEN | ENSOCUP00000015360 | ENSOCUP00000007574 | Annexin. | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. | 0.466 |