STRINGSTRING
ACTA1 ACTA1 PGAM1 PGAM1 PAX7 PAX7 ACTC1 ACTC1 MYO1D MYO1D PTEN PTEN LMNA LMNA MYH8 MYH8 TNNI1 TNNI1 MYOG MYOG MTOR MTOR FOXO1 FOXO1 PAX3 PAX3 ANXA3 ANXA3 ZEB2 ZEB2 NEFL NEFL MYH1 MYH1 RPL13A RPL13A SPP1 SPP1 MYF5 MYF5 NOTCH3 NOTCH3 ZBTB20 ZBTB20 GAPDH GAPDH BMP6 BMP6 TSHZ2 TSHZ2 TNNT3 TNNT3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACTA1Actin, alpha skeletal muscle. (369 aa)
PGAM1Uncharacterized protein. (129 aa)
PAX7Paired box 7. (476 aa)
ACTC1Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. (377 aa)
MYO1DMyosin ID; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1021 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (704 aa)
MYH8Myosin heavy chain 8; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1937 aa)
TNNI1Troponin I, slow skeletal muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. (187 aa)
MYOGMyogenin. (225 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2547 aa)
FOXO1Fork-head domain-containing protein. (613 aa)
PAX3Paired box 3. (484 aa)
ANXA3Annexin. (323 aa)
ZEB2Zinc finger E-box binding homeobox 2. (1188 aa)
NEFLNeurofilament light; Belongs to the intermediate filament family. (548 aa)
MYH1Myosin-4; Muscle contraction. (1938 aa)
RPL13AUncharacterized protein. (135 aa)
SPP1Osteopontin; Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction; Belongs to the osteopontin family. (311 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
NOTCH3Notch receptor 3. (2262 aa)
ZBTB20Zinc finger and BTB domain containing 20. (741 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (333 aa)
BMP6Bone morphogenetic protein 6. (411 aa)
TSHZ2Teashirt zinc finger homeobox 2. (1036 aa)
TNNT3Troponin T, fast skeletal muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. (202 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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