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SLC4A8 SLC4A8 PXDNL PXDNL SLC4A10 SLC4A10 CA9 CA9 CPT2 CPT2 SLC4A5 SLC4A5 PXDN PXDN CA12 CA12 CA2 CA2 SLC4A7 SLC4A7 SLC4A1 SLC4A1 CFTR CFTR CA13 CA13 PPARG PPARG CA4 CA4 HDAC6 HDAC6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SLC4A8Anion exchange protein. (1027 aa)
PXDNLPeroxidasin like. (1467 aa)
SLC4A10Anion exchange protein. (1118 aa)
CA9Carbonic anhydrase 9; Belongs to the alpha-carbonic anhydrase family. (435 aa)
CPT2Carnitine palmitoyltransferase 2; Belongs to the carnitine/choline acetyltransferase family. (609 aa)
SLC4A5Anion exchange protein. (1112 aa)
PXDNPeroxidasin. (1411 aa)
CA12Carbonic anhydrase 12; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. (372 aa)
CA2Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6 (By similarity). Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. (269 aa)
SLC4A7Anion exchange protein. (1249 aa)
SLC4A1Anion exchange protein. (981 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1481 aa)
CA13Carbonic anhydrase 13; Belongs to the alpha-carbonic anhydrase family. (263 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
CA4Carbonic anhydrase 4; Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 (By similarity). (416 aa)
HDAC6Histone deacetylase 6. (1257 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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