STRINGSTRING
CDKN2B CDKN2B LOC100357927 LOC100357927 IKZF1 IKZF1 H3F3B H3F3B SYNDIG1L SYNDIG1L ETV6 ETV6 JAK2 JAK2 H3C13 H3C13 LOC100345683 LOC100345683 CXCR5 CXCR5 H3-3A H3-3A MEOX2 MEOX2 LOC100344410 LOC100344410 RAG1 RAG1 RAG2 RAG2 LOC100340625 LOC100340625 TBP TBP G1TX56_RABIT G1TX56_RABIT G1TJR7_RABIT G1TJR7_RABIT BCL2 BCL2 CD19 CD19 SEMA4A SEMA4A IL7 IL7 ENSOCUP00000042583 ENSOCUP00000042583 GAPDH GAPDH EBF1 EBF1 JAK1 JAK1 FLT3 FLT3 BRD1 BRD1 LMO2 LMO2 HNRNPLL HNRNPLL NOL4L NOL4L PAX5 PAX5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CDKN2BCyclin dependent kinase inhibitor 2B. (138 aa)
LOC100357927Histone domain-containing protein. (136 aa)
IKZF1IKAROS family zinc finger 1. (515 aa)
H3F3BHistone H3; Belongs to the histone H3 family. (136 aa)
SYNDIG1LSynapse differentiation inducing 1 like. (238 aa)
ETV6ETS variant 6. (508 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
H3C13Histone H3; Belongs to the histone H3 family. (136 aa)
LOC100345683Histone H3; Belongs to the histone H3 family. (136 aa)
CXCR5C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family. (374 aa)
H3-3AHistone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...] (136 aa)
MEOX2Mesenchyme homeobox 2. (303 aa)
LOC100344410Histone domain-containing protein. (136 aa)
RAG1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1128 aa)
RAG2V(D)J recombination-activating protein 2; Core component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T- cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. DNA cleavage by the RAG complex occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the pho [...] (527 aa)
LOC100340625ANK_REP_REGION domain-containing protein. (324 aa)
TBPTATA-box binding protein. (323 aa)
G1TX56_RABITHistone H3; Belongs to the histone H3 family. (136 aa)
G1TJR7_RABITHistone H3; Belongs to the histone H3 family. (136 aa)
BCL2BH4_2 domain-containing protein. (389 aa)
CD19CD19 molecule. (573 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (977 aa)
IL7Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (175 aa)
ENSOCUP00000042583Histone H3; Belongs to the histone H3 family. (115 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (333 aa)
EBF1EBF transcription factor 1. (591 aa)
JAK1Tyrosine-protein kinase. (1151 aa)
FLT3Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (993 aa)
BRD1Bromodomain containing 1. (1090 aa)
LMO2LIM domain only 2. (158 aa)
HNRNPLLHeterogeneous nuclear ribonucleoprotein L like. (541 aa)
NOL4LNucleolar protein 4 like. (680 aa)
PAX5Paired box 5. (371 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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