STRINGSTRING
TNFRSF21 TNFRSF21 PTPRK PTPRK CD44 CD44 SYVN1 SYVN1 PGF PGF NPR1 NPR1 PXDN PXDN VTN VTN ITGA2 ITGA2 ANO6 ANO6 ITGA6 ITGA6 PTK7 PTK7 JAG1 JAG1 SCARB2 SCARB2 LIF LIF SMARCA4 SMARCA4 NRP1 NRP1 FUT8 FUT8 CNTF CNTF PXDNL PXDNL CTF1 CTF1 CDCP1 CDCP1 ITGA3 ITGA3 OSM OSM EGFR EGFR STAT3 STAT3 OSMR OSMR ITGA5 ITGA5 ITGB5 ITGB5 PGR PGR AXL AXL IL6 IL6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TNFRSF21TNF receptor superfamily member 21. (655 aa)
PTPRKProtein tyrosine phosphatase receptor type K. (1472 aa)
CD44CD44 molecule (Indian blood group). (761 aa)
SYVN1Synoviolin 1. (678 aa)
PGFPlacental growth factor; Belongs to the PDGF/VEGF growth factor family. (170 aa)
NPR1Guanylate cyclase. (1056 aa)
PXDNPeroxidasin. (1411 aa)
VTNVitronectin; Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway. (475 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1202 aa)
ANO6Anoctamin. (1003 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (955 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (978 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
SCARB2Scavenger receptor class B member 2; Belongs to the CD36 family. (478 aa)
LIFLIF interleukin 6 family cytokine. (203 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1653 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (950 aa)
FUT8Alpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. Belongs to the glycosyltransferase 23 family. (602 aa)
CNTFCiliary neurotrophic factor; CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy. (199 aa)
PXDNLPeroxidasin like. (1467 aa)
CTF1Cardiotrophin 1. (190 aa)
CDCP1CUB domain containing protein 1. (840 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1072 aa)
OSMUncharacterized protein. (333 aa)
EGFRReceptor protein-tyrosine kinase. (1193 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
OSMROncostatin M receptor. (1088 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1105 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (799 aa)
PGRProgesterone receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcriptional activator of several progesteron-dependent promoters in a variety of cell types. Involved in activation of SRC-dependent MAPK signaling on hormone stimulation; Belongs to the nuclear hormone receptor family. NR3 subfamily. (930 aa)
AXLAXL receptor tyrosine kinase. (625 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (241 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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