20 items (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MYOG	Myogenin. (225 aa)
	CCNB2	Cyclin B2; Belongs to the cyclin family. (398 aa)
	TNNT3	Troponin T, fast skeletal muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. (202 aa)
	MYH7B	Myosin heavy chain 7B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1982 aa)
	MYH8	Myosin heavy chain 8; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1937 aa)
	TNNI1	Troponin I, slow skeletal muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. (187 aa)
	CDKN1B	Cyclin dependent kinase inhibitor 1B. (198 aa)
	ACACA	Acetyl-CoA carboxylase alpha. (2383 aa)
	OXSM	3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (460 aa)
	CCND2	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (431 aa)
	CDKN1A	Uncharacterized protein. (231 aa)
	MYH1	Myosin-4; Muscle contraction. (1938 aa)
	MCAT	Malonyl-CoA-acyl carrier protein transacylase. (466 aa)
	MYH7	Myosin-7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1935 aa)
	MB	Myoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. (106 aa)
	ULK1	Unc-51 like autophagy activating kinase 1. (1001 aa)
	COX2	Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (227 aa)
	ZFP36L2	ZFP36 ring finger protein like 2. (467 aa)
	SOX6	SRY-box transcription factor 6. (855 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (333 aa)

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACACA	GAPDH	ENSOCUP00000012460	ENSOCUP00000044112	Acetyl-CoA carboxylase alpha.	Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...]	0.505
ACACA	MCAT	ENSOCUP00000012460	ENSOCUP00000021054	Acetyl-CoA carboxylase alpha.	Malonyl-CoA-acyl carrier protein transacylase.	0.980
ACACA	OXSM	ENSOCUP00000012460	ENSOCUP00000013210	Acetyl-CoA carboxylase alpha.	3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.783
CCNB2	CCND2	ENSOCUP00000001415	ENSOCUP00000013388	Cyclin B2; Belongs to the cyclin family.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.451
CCNB2	CDKN1A	ENSOCUP00000001415	ENSOCUP00000013788	Cyclin B2; Belongs to the cyclin family.	Uncharacterized protein.	0.783
CCNB2	CDKN1B	ENSOCUP00000001415	ENSOCUP00000012008	Cyclin B2; Belongs to the cyclin family.	Cyclin dependent kinase inhibitor 1B.	0.671
CCNB2	GAPDH	ENSOCUP00000001415	ENSOCUP00000044112	Cyclin B2; Belongs to the cyclin family.	Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...]	0.577
CCND2	CCNB2	ENSOCUP00000013388	ENSOCUP00000001415	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cyclin B2; Belongs to the cyclin family.	0.451
CCND2	CDKN1A	ENSOCUP00000013388	ENSOCUP00000013788	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein.	0.996
CCND2	CDKN1B	ENSOCUP00000013388	ENSOCUP00000012008	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cyclin dependent kinase inhibitor 1B.	0.999
CCND2	GAPDH	ENSOCUP00000013388	ENSOCUP00000044112	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...]	0.771
CCND2	MYOG	ENSOCUP00000013388	ENSOCUP00000009928	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Myogenin.	0.427
CDKN1A	CCNB2	ENSOCUP00000013788	ENSOCUP00000001415	Uncharacterized protein.	Cyclin B2; Belongs to the cyclin family.	0.783
CDKN1A	CCND2	ENSOCUP00000013788	ENSOCUP00000013388	Uncharacterized protein.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.996
CDKN1A	CDKN1B	ENSOCUP00000013788	ENSOCUP00000012008	Uncharacterized protein.	Cyclin dependent kinase inhibitor 1B.	0.976
CDKN1A	GAPDH	ENSOCUP00000013788	ENSOCUP00000044112	Uncharacterized protein.	Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...]	0.694
CDKN1A	MYOG	ENSOCUP00000013788	ENSOCUP00000009928	Uncharacterized protein.	Myogenin.	0.405
CDKN1B	CCNB2	ENSOCUP00000012008	ENSOCUP00000001415	Cyclin dependent kinase inhibitor 1B.	Cyclin B2; Belongs to the cyclin family.	0.671
CDKN1B	CCND2	ENSOCUP00000012008	ENSOCUP00000013388	Cyclin dependent kinase inhibitor 1B.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.999
CDKN1B	CDKN1A	ENSOCUP00000012008	ENSOCUP00000013788	Cyclin dependent kinase inhibitor 1B.	Uncharacterized protein.	0.976