STRINGSTRING
CD4 CD4 MYL3 MYL3 TCF24 TCF24 MYL4 MYL4 MYL1 MYL1 HOXD8 HOXD8 METTL21C METTL21C GSN GSN ANO5 ANO5 HOXA13 HOXA13 LTK LTK PDGFRA PDGFRA MYH4 MYH4 TGFB2 TGFB2 LUM LUM G1SV95_RABIT G1SV95_RABIT CD68 CD68 TBX5 TBX5 COL1A1 COL1A1 APCS APCS IL21 IL21 HAND2 HAND2 ANO3 ANO3 MYH1 MYH1 SGCA SGCA HOXD9 HOXD9 ADIPOQ ADIPOQ MYH7 MYH7 SPP1 SPP1 JCHAIN JCHAIN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CD4T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (536 aa)
MYL3Myosin light chain 3. (327 aa)
TCF24Transcription factor 24. (167 aa)
MYL4Myosin light chain 4. (230 aa)
MYL1Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. (193 aa)
HOXD8Homeobox domain-containing protein. (106 aa)
METTL21CMethyltransferase like 21C. (331 aa)
GSNGelsolin. (828 aa)
ANO5Anoctamin. (1040 aa)
HOXA13Homeobox A13. (222 aa)
LTKTyrosine-protein kinase receptor. (865 aa)
PDGFRAProtein kinase domain-containing protein. (773 aa)
MYH4Myosin-4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1939 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
LUMLumican. (338 aa)
G1SV95_RABITTransforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
CD68CD68 molecule. (334 aa)
TBX5T-box transcription factor 5. (518 aa)
COL1A1Collagen alpha-1(I) chain. (1348 aa)
APCSPentaxin. (223 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (154 aa)
HAND2BHLH domain-containing protein. (426 aa)
ANO3Anoctamin. (981 aa)
MYH1Myosin-4; Muscle contraction. (1938 aa)
SGCAAlpha-sarcoglycan; Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. (440 aa)
HOXD9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (248 aa)
ADIPOQC1q domain-containing protein. (244 aa)
MYH7Myosin-7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1935 aa)
SPP1Osteopontin; Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction; Belongs to the osteopontin family. (311 aa)
JCHAINImmunoglobulin J chain; Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component. (158 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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